Optimized Palladium（0）-catalyzed Suzuki Cross-coupling Reaction of Polystyrene-supported Selenenyl Flavanones： A Convenient Preparation of Biaryl-chromen-4-one

Application of the Suzuki cross-coupling reaction for efficient synthesis of diverse substituted biaryl-chromen- 4-ones using an optimized palladium（0） catalyst system is reported. The coupling of arylboronic acids with the resin-bound bromoflavanones which were prepared by organoselenium-induced regioselective intramolecular cy- clization of bromo-2-hydroxylchalcones proceeded smoothly. Biaryl-chromen-4-ones were synthesized by subse- quent selenoxide syn-elimination in good total yields.