Kinetic study on the reaction of cis-[Pd（en）（H2O）2]（NO3）2 and N-AcCysMe

Kinetic study on the reaction of cis-[Pd（en）（H2O）2]（NO3）2 and N-AcCysMe

Over the years, there has been a great deal of interest in developing artificial enzymesthat hydrolyse amide bond of peptides and proteins. Recently, we found that Pd(Ⅱ)complexes bind to the sulfur atom of S-methylcysteine or methionine in peptides andpromote the selective hydrolysis of the adjacent...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:中国科学通报：英文版 1996 (5), p.390-394
1. Verfasser: 陈晓华 朱龙根 燕红 N.M.Kostic 游效曾
Format: Artikel
Sprache:eng
Schlagworte:
cis-[Pd(en)(H2O)2](NO3)2
kinetics
N-AcCysMe
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Over the years, there has been a great deal of interest in developing artificial enzymesthat hydrolyse amide bond of peptides and proteins. Recently, we found that Pd(Ⅱ)complexes bind to the sulfur atom of S-methylcysteine or methionine in peptides andpromote the selective hydrolysis of the adjacent amide bond on the carboxyl side of an-choring side chain. The half-lives of certain hydrolysis reactions are as short as several
ISSN:2095-9273