KAl(SO4)2·12H2O catalyzed efficient synthesis of 3,4,6-trisubstituted 2-pyridone in water

An efficient green protocol for the preparation 3,4,6-trisubstituted 2-pyridone of employing a condensation reaction of cyanoacetamide and acetylacetone in the presence of KAl(SO4)2·12H2O in water has been described. The present procedure offers advantage such as shorter reaction time, simple workup...

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Veröffentlicht in:中国化学快报:英文版 2011, Vol.22 (9), p.1059-1062
1. Verfasser: Majid M. Heravi Hossein A. Oskooie Narges Karimi Hoda Hamidi
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Sprache:eng
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Zusammenfassung:An efficient green protocol for the preparation 3,4,6-trisubstituted 2-pyridone of employing a condensation reaction of cyanoacetamide and acetylacetone in the presence of KAl(SO4)2·12H2O in water has been described. The present procedure offers advantage such as shorter reaction time, simple workup, and excellent yields.
ISSN:1001-8417
1878-5964