THE EXPRESSION OF ENTEROTOXIN A~-B~+ GENE OF V. cholerae IN E. coli

The cloning in E. coli of a cholerae toxin gene that is A~-B~+ has been successfully constructed by using DNA recombinant techniques. E. coli cells carrying the recombinant plasmid pMM-CTB have been shown to produce a large amount of CTB subunits which are secreted as extracellular proteins.

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Veröffentlicht in:中国科学:化学英文版 1989 (2), p.186-192
1. Verfasser: 马清钧 周建光 于秀琴 刘传暄 熊凌霜 徐永强 黄翠芬
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Sprache:eng
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Zusammenfassung:The cloning in E. coli of a cholerae toxin gene that is A~-B~+ has been successfully constructed by using DNA recombinant techniques. E. coli cells carrying the recombinant plasmid pMM-CTB have been shown to produce a large amount of CTB subunits which are secreted as extracellular proteins.
ISSN:1674-7291
1869-1870