BIOCHEMICAL AND CIRCLING BEHAVIORAL ALTERATIONS FOLLOWING INJECTION OF MPTP INTO SNC IN RAT

BIOCHEMICAL AND CIRCLING BEHAVIORAL ALTERATIONS FOLLOWING INJECTION OF MPTP INTO SNC IN RAT

MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine) is a byproduct formed during the synthesis of a meperidine analog. Davis (1979) and Langston (1983) reported a group of drug addicts who developed classical Parkinsonism after self-administration of a mixture containing MPTP, their pathological...

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Veröffentlicht in:中国科学通报：英文版 1989 (8), p.683-687
1. Verfasser: 乐卫东 周孝达 金国章 许守玺
Format: Artikel
Sprache:eng
Schlagworte:
behavioar
catecholamine
circling
MPTP
receptor
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Zusammenfassung:MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine) is a byproduct formed during the synthesis of a meperidine analog. Davis (1979) and Langston (1983) reported a group of drug addicts who developed classical Parkinsonism after self-administration of a mixture containing MPTP, their pathological and biochemical changes
ISSN:2095-9273