Synthesis of 0,0-diethyl-α-(p-toluenesulphonamido) phosphonates by Mannich-type reaction

A series of O,O-diethyl-α-（p-toluenesulphonamido）phosphonates have been synthesized by theMannich-type reaction of p-toluenesulphonamide,substituted benzaldehydes and diethyl phosphite with acetylchloride as the solvent.The mechanism of the reaction is suggested,and the structures of new products areconfirmed by 1H NMR,31p NMR,elemental analysis and X-ray diffraction.The results of preliminarybioassay showed that some of them possess herbicidal activities.