THE IMMUNOREGULATORY EFFECT OF TLSFJM ON THE EXPRESSION OF T CELL IL-2R AND PROTEIN TYROSINE PHOSPHORYLATION

THE IMMUNOREGULATORY EFFECT OF TLSFJM ON THE EXPRESSION OF T CELL IL-2R AND PROTEIN TYROSINE PHOSPHORYLATION

The immunoregulatory effect of TLSFJM on the expression of T cell IL- 2R and protein tyrosine phosphorylation ( PTP ) was investigated by immunohistochemistry technique. The results showed that TLSFJMcan markedly suppress the expression of IL-2R and PTP on PHA or TPA-stimulated human PBMC and murine...

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Veröffentlicht in:中国癌症研究：英文版 1991 (4), p.10-15
1. Verfasser: 夏海滨 金伯泉 许辉 赵宁 刘雪松 黄传书 朱勇 李恩善
Format: Artikel
Sprache:eng
Schlagworte:
activation
factor
immunoregulation
inhibitory
lymphocyte
phosphorylation
protein
tyrosine
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Zusammenfassung:The immunoregulatory effect of TLSFJM on the expression of T cell IL- 2R and protein tyrosine phosphorylation ( PTP ) was investigated by immunohistochemistry technique. The results showed that TLSFJMcan markedly suppress the expression of IL-2R and PTP on PHA or TPA-stimulated human PBMC and murine IL-2 dependent cell line CTLL-2. However, there was no effect of TLSFJMon the production of IL-1, IL-2 and IL-6 that play an important role in the course of T lymphocyte proliferation and differentiation.
ISSN:1000-9604
1993-0631