THE FORMATION AND CRYSTAL STRUCTURE OF DIHYDRONITIDINE AND DISCUSSION OF ANTICANCER MECHANISM OF NITIDINE CATION

The paper reports the formation and crystal structure of dihydronitidine, expounds thereasons and conditions of easily formed oxynitidine, and discusses anticancer mechanism ofnitidine （cation）. The crystallographic parameters of dihydronitidine are: space group P21/n,a= 12.54（1）, b = 9. 148（5）, c = 14.748（8）A, β= 92. 12（6）°,Z =4. 4108 independent reflec-tions were collected within the range of 3°≤2θ≤54°, of which 2137 intensity data with I≥3σ（I） were used in the structural determination. The crystal structure has been refined byfull matrix least-square method to a final R of 0.050.