STUDIES ON PEPTIDES (Ⅵ)——SYNTHESIS AND PRIMARY BIOLOGICAL ACTIVITY EXAMINING OF THREE FRAGMENTS (93-102, 84-102, 25-38) OF TRANSFORMING GROWTH FACTOR-β

STUDIES ON PEPTIDES (Ⅵ)——SYNTHESIS AND PRIMARY BIOLOGICAL ACTIVITY EXAMINING OF THREE FRAGMENTS (93-102, 84-102, 25-38) OF TRANSFORMING GROWTH FACTOR-β

Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have synthesized a series of its important fragments by manual stepwise solid-phase method...

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Veröffentlicht in:中国科学通报：英文版 1992 (13), p.1116-1120
1. Verfasser: 田少雷 蔡孟深 赵明 张肇康
Format: Artikel
Sprache:eng
Schlagworte:
factor-β
growth
HPLC
peptides
solid-phase
synthesis
transforming
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Zusammenfassung:Transforming growth factor-β(TGF-β)is a multifunctional regulatory molecule existing in a wide variety of both normal and neoplastic cells. In order to evaluate the structure-function relationship of TGF-β, we have synthesized a series of its important fragments by manual stepwise solid-phase methodology and studied their biological activity. In this
ISSN:2095-9273