Antiarthritic effects of Ajuga bracteosa Wall ex Benth.in acute and chronic models of arthritis in albino rats

Objective:To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.Methods: The antiarthritic activity of 70%ethanolic extract of Ajuga bracteosa(EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund’s adjuvant(CFA)-induced chronic immunological arthritis in albino rats.Results:EEAB showed a significant(P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis.EEAB exhibited better antiarthritic activity than the standard aspirin.Conclusions: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.