[BMIM]CI Catalyzed One-Pot Synthesis of a-Aminophospho- nate Derivatives Containing a 4-Phenoxyquinazoline Moiety under Microwave Irradiation

[BMIM]Cl catalyzed three component Mannich-type reaction of 4-(quinazolin-4-yloxy)benzenamine and aldehyde with dialkyl phosphite under microwave irradiation has been described. The salient features of the reaction leading to new a-aminophosphonates include shorter reaction time and good yields. The...

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Veröffentlicht in:Chinese journal of chemistry 2011, Vol.29 (1), p.109-117
1. Verfasser: Bai, Song Song, Baoan Bhadury, Pinaki S. Yang, Song Hu, Deyu Xue, Wei
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Sprache:eng
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Zusammenfassung:[BMIM]Cl catalyzed three component Mannich-type reaction of 4-(quinazolin-4-yloxy)benzenamine and aldehyde with dialkyl phosphite under microwave irradiation has been described. The salient features of the reaction leading to new a-aminophosphonates include shorter reaction time and good yields. The method is environmentally friendly and does not require toxic catalysts or solvents. To the best of our knowledge, this is the first report for [BMIM]Cl induced one-pot synthesis of a-aminophosphonate derivatives.
ISSN:1001-604X
1614-7065