rasing fear memories- key receptor and essential :imeframe discovered

It is clinically important to suppress or inhibit traumatic memories, which are formed after fearful experiences. In animal models, fear memory is formed by repetitive presentation of a tone paired with an electrical foot-shock. It is well known that an extinction protocol, in which the tone is repe...

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Veröffentlicht in:Acta pharmacologica Sinica 2011, Vol.32 (1), p.1-2
1. Verfasser: Shigenori KAWAHARA
Format: Artikel
Sprache:eng
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Zusammenfassung:It is clinically important to suppress or inhibit traumatic memories, which are formed after fearful experiences. In animal models, fear memory is formed by repetitive presentation of a tone paired with an electrical foot-shock. It is well known that an extinction protocol, in which the tone is repeatedly presented without the foot-shock, gradually decreases the preacquired fear response to the tone. However, this fear extinction protocol is not sufficient to erase the fear memory;
ISSN:1671-4083
1745-7254