Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China

Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China

Background and objective To study the clinicopathological characteristics of Lynch syndrome-associated endometrial carcinoma in China. Methods Twenty-seven patients who fulfilled the Amsterdam Criteria II were classified as having Lynch syndrome-associated endometrial carcinoma （Group A）, and 331 pa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Zhongguo fei ai za zhi 2009, Vol.12 (6), p.700-705
1. Verfasser: Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU
Format: Artikel
Sprache:chi
Schlagworte:
治疗
疗效
癌细胞
肺癌
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 705
container_issue 6
container_start_page 700
container_title Zhongguo fei ai za zhi
container_volume 12
creator Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU
description Background and objective To study the clinicopathological characteristics of Lynch syndrome-associated endometrial carcinoma in China. Methods Twenty-seven patients who fulfilled the Amsterdam Criteria II were classified as having Lynch syndrome-associated endometrial carcinoma （Group A）, and 331 patients without a family history of cancer were classified as having sporadic endometrial carcinoma （Group B）. Results There were 81 malignancies in 27 Lynch syndrome-associated endometrial carcinoma families, including colorectal cancer （CRC, 24.7%）, endometrial carcinoma （21.0%）, liver （12.3%）, stomach （9.9%）, lung （6.2%）, and breast （6.2%） cancers. Mean age at time of diagnosis was 49.7 years in Group A and 56.3 years in Group B （P=0.004）. Second primary cancers occurred in 33.3% of patients in Group A and 5.1% in Group B （P〈0.0001）. The most common second primary cancers were colorectal cancer （44%） and ovarian cancer （22%）. The percentage of obese patients was higher in Group A （P=0.013）. There was no differenc
format Article
fullrecord <record><control><sourceid>chongqing</sourceid><recordid>TN_cdi_chongqing_backfile_30899739</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>30899739</cqvip_id><sourcerecordid>30899739</sourcerecordid><originalsourceid>FETCH-chongqing_backfile_308997393</originalsourceid><addsrcrecordid>eNqNisFqwkAQQBepYGj9h8F7YJNYdY4lGDz01l5LmGw22cF1tmZXxL83h35AT-_xeAuVFYiY74rD_mV2rTGvtgWu1DpG7rQuy12J-j1TP7VnYRN-Kbngw8iGPDSW0m2yEcIAR-nDxaaJ517TZFjCheAjxmCYku3hzsnB50OMg6-H9NN8AwvUjoXe1HIgH-36j69q0xy_61NuXJDxyjK2HZnzwN62lT4g7ius_jU9AX1PRWk</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</creator><creatorcontrib>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</creatorcontrib><description>Background and objective To study the clinicopathological characteristics of Lynch syndrome-associated endometrial carcinoma in China. Methods Twenty-seven patients who fulfilled the Amsterdam Criteria II were classified as having Lynch syndrome-associated endometrial carcinoma （Group A）, and 331 patients without a family history of cancer were classified as having sporadic endometrial carcinoma （Group B）. Results There were 81 malignancies in 27 Lynch syndrome-associated endometrial carcinoma families, including colorectal cancer （CRC, 24.7%）, endometrial carcinoma （21.0%）, liver （12.3%）, stomach （9.9%）, lung （6.2%）, and breast （6.2%） cancers. Mean age at time of diagnosis was 49.7 years in Group A and 56.3 years in Group B （P=0.004）. Second primary cancers occurred in 33.3% of patients in Group A and 5.1% in Group B （P〈0.0001）. The most common second primary cancers were colorectal cancer （44%） and ovarian cancer （22%）. The percentage of obese patients was higher in Group A （P=0.013）. There was no differenc</description><identifier>ISSN: 1009-3419</identifier><identifier>EISSN: 1999-6187</identifier><language>chi</language><subject>治疗 ; 疗效 ; 癌细胞 ; 肺癌</subject><ispartof>Zhongguo fei ai za zhi, 2009, Vol.12 (6), p.700-705</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/91098A/91098A.jpg</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids></links><search><creatorcontrib>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</creatorcontrib><title>Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China</title><title>Zhongguo fei ai za zhi</title><addtitle>Chinese Journal of Lung Cancer</addtitle><description>Background and objective To study the clinicopathological characteristics of Lynch syndrome-associated endometrial carcinoma in China. Methods Twenty-seven patients who fulfilled the Amsterdam Criteria II were classified as having Lynch syndrome-associated endometrial carcinoma （Group A）, and 331 patients without a family history of cancer were classified as having sporadic endometrial carcinoma （Group B）. Results There were 81 malignancies in 27 Lynch syndrome-associated endometrial carcinoma families, including colorectal cancer （CRC, 24.7%）, endometrial carcinoma （21.0%）, liver （12.3%）, stomach （9.9%）, lung （6.2%）, and breast （6.2%） cancers. Mean age at time of diagnosis was 49.7 years in Group A and 56.3 years in Group B （P=0.004）. Second primary cancers occurred in 33.3% of patients in Group A and 5.1% in Group B （P〈0.0001）. The most common second primary cancers were colorectal cancer （44%） and ovarian cancer （22%）. The percentage of obese patients was higher in Group A （P=0.013）. There was no differenc</description><subject>治疗</subject><subject>疗效</subject><subject>癌细胞</subject><subject>肺癌</subject><issn>1009-3419</issn><issn>1999-6187</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqNisFqwkAQQBepYGj9h8F7YJNYdY4lGDz01l5LmGw22cF1tmZXxL83h35AT-_xeAuVFYiY74rD_mV2rTGvtgWu1DpG7rQuy12J-j1TP7VnYRN-Kbngw8iGPDSW0m2yEcIAR-nDxaaJ517TZFjCheAjxmCYku3hzsnB50OMg6-H9NN8AwvUjoXe1HIgH-36j69q0xy_61NuXJDxyjK2HZnzwN62lT4g7ius_jU9AX1PRWk</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope></search><sort><creationdate>2009</creationdate><title>Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China</title><author>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_backfile_308997393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2009</creationdate><topic>治疗</topic><topic>疗效</topic><topic>癌细胞</topic><topic>肺癌</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>Zhongguo fei ai za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yingmei WANG Fengxia XUE Russell R. BROADDUS Xia TAO Susu XIE Yanbin ZHU</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China</atitle><jtitle>Zhongguo fei ai za zhi</jtitle><addtitle>Chinese Journal of Lung Cancer</addtitle><date>2009</date><risdate>2009</risdate><volume>12</volume><issue>6</issue><spage>700</spage><epage>705</epage><pages>700-705</pages><issn>1009-3419</issn><eissn>1999-6187</eissn><abstract>Background and objective To study the clinicopathological characteristics of Lynch syndrome-associated endometrial carcinoma in China. Methods Twenty-seven patients who fulfilled the Amsterdam Criteria II were classified as having Lynch syndrome-associated endometrial carcinoma （Group A）, and 331 patients without a family history of cancer were classified as having sporadic endometrial carcinoma （Group B）. Results There were 81 malignancies in 27 Lynch syndrome-associated endometrial carcinoma families, including colorectal cancer （CRC, 24.7%）, endometrial carcinoma （21.0%）, liver （12.3%）, stomach （9.9%）, lung （6.2%）, and breast （6.2%） cancers. Mean age at time of diagnosis was 49.7 years in Group A and 56.3 years in Group B （P=0.004）. Second primary cancers occurred in 33.3% of patients in Group A and 5.1% in Group B （P〈0.0001）. The most common second primary cancers were colorectal cancer （44%） and ovarian cancer （22%）. The percentage of obese patients was higher in Group A （P=0.013）. There was no differenc</abstract></addata></record>
fulltext fulltext
identifier ISSN: 1009-3419
ispartof Zhongguo fei ai za zhi, 2009, Vol.12 (6), p.700-705
issn 1009-3419
1999-6187
language chi
recordid cdi_chongqing_backfile_30899739
source DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects 治疗
疗效
癌细胞
肺癌
title Clinicopathological Features of Endometrial Carcinoma Associated with Lynch Syndrome in China
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T23%3A25%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-chongqing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinicopathological%20Features%20of%20Endometrial%20Carcinoma%20Associated%20with%20Lynch%20Syndrome%20in%20China&rft.jtitle=Zhongguo%20fei%20ai%20za%20zhi&rft.au=Yingmei%20WANG%20Fengxia%20XUE%20Russell%20R.%20BROADDUS%20Xia%20TAO%20Susu%20XIE%20Yanbin%20ZHU&rft.date=2009&rft.volume=12&rft.issue=6&rft.spage=700&rft.epage=705&rft.pages=700-705&rft.issn=1009-3419&rft.eissn=1999-6187&rft_id=info:doi/&rft_dat=%3Cchongqing%3E30899739%3C/chongqing%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=30899739&rfr_iscdi=true