Lewy body dementia versus Psychosis in Parkinson’s disease. A case of temporal evolution of psychosis and motor symptoms

Lewy body dementia and Psychosis in Parkinson's disease have not only similar anatomic characteristics, both entities being categorized as alpha-synupleinopathies, but they also have in common clinical manifestations. Moreover, in recent years, the diagnostic criteria for both Lewy-body Dementia and Parkinson's-related Psychosis have been attempted and it has been noticed that the chronology of symptomatology is essential in differentiating them. Although it is considered that the differential diagnosis between the two conditions is especially important for the field research, it is necessary to know and to distinguish them in order to establish an appropriate treatment. For example, as early as 2016, there are ongoing studies on the effectiveness of Pimavanserin in the treatment of Psychosis in Parkinson's disease. Additionally, diagnostic accuracy and certainty will increase significantly with the development of imaging techniques. Diagnostic certainty is currently possible only anatomopathologically. The presented case reveals the need for an interdisciplinary collaboration - neurologist - psychiatrist - radiologist, in order to establish a precise diagnosis which facilitates the therapeutic management of psychoproductive phenomenology (necessary to improve the quality of the patient's life).