O-027 The INVEST Trial: A Randomized, Controlled Trial to Investigate the Safety and Efficacy of Image Guided Minimally Invasive Endoscopic Surgery with Apollo vs Best Medical Management for Supratentorial Intracerebral Hemorrhage

IntroductionSpontaneous intracerebral hemorrhage (ICH) is a common subtype of hemorrhagic stroke, and has the poorest prognosis amongst all stroke subtypes. The goal of the INVEST trial, as well the parallel European EPOCH trial, is to evaluate the safety and efficacy of the minimally invasive hemorrhage evacuation with Apollo device (Penumbra Inc, Alameda, CA) compared to medical management.MethodsThe INVEST study is a prospective multicenter US trial designed to enroll 222 patients at up to 30 centers. The parallel European EPOCH study is a 240 patient, 40 center RCT. Patients between the ages of 22–80 or