Ovarian Cancer in Ghana, a 10 Year Histopathological Review of Cases at Korle Bu Teaching Hospital
To determine the histopathological types, age distribution, presenting signs and symptoms of ovarian cancers diagnosed at the Korle-Bu Teaching Hospital, Ghana. All histopathology slides and request cards of ovarian cancers diagnosed over a ten-year period (2001 to 2010) were reviewed and the cancer...
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Veröffentlicht in: | African journal of reproductive health 2016-02, Vol.4 (12) |
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Zusammenfassung: | To determine the histopathological types, age distribution, presenting
signs and symptoms of ovarian cancers diagnosed at the Korle-Bu
Teaching Hospital, Ghana. All histopathology slides and request cards
of ovarian cancers diagnosed over a ten-year period (2001 to 2010) were
reviewed and the cancers classified according to the World Health
Organization 1999 classification. Biographical and clinical data of the
patients were collected and results entered into Epi-info to determine
the frequency, age distribution and clinical presentation of the
various types of ovarian cancer. There were 192(27.2%) ovarian cancers
out of 706 ovarian tumours. Epithelial cancers were the most common:
100 (52.1%), followed by sex cord stromal cancers 66 (34.4%). Majority
of epithelial cancers were serous adenocarcinomas (71/100) while most
sex cord stromal cancers were adult granulosa cell tumours 46 (69.7%).
The mean age of patients with adenocarcinoma was 49 years while that of
the 46 adult granulosa cell tumours was 46.5years. Patients present
with varying combinations of symptoms and signs and ovarian cancers
present at an earlier age compared to other populations, with the age
of presentation being slightly lower for sex cord stromal cancers
compared to adenocarcinomas. There are no specific symptoms or signs
associated with ovarian cancer at presentation, to assist with
diagnosis.
Afin de déterminer les types, la distribution d'âge, les
signes et les symptômes de la présentation histopathologiques
de cancers de l'ovaire qui ont été diagnostiqués au
Centre Hospitalier Universitaire de Korle-Bu, au Ghana, toutes les
diapositifs d'histopathologiques et les cartes de demande de cancers de
l'ovaire diagnostiqués au cours d'une période de dix
ans (2001 à 2010) ont été examinés et les cancers
classés selon la classification de l'Organisation mondiale de la
Santé de1999. Les données biographiques et cliniques des
patientes ont été recueillies et les résultats
enregistrés dans Epi-info pour déterminer la fréquence,
la distribution de l'âge et de la présentation clinique des
différents types de cancer de l'ovaire. Il y avait 192 (27,2%)
cancers de l'ovaire sur 706 tumeurs ovariennes. Les cancers
épithéliaux étaient les plus courantes: 100 (52,1%),
suivi par les cancers du stroma des cordons sexuels 66 (34,4%). La
majorité des cancers épithéliaux étaient
adénocarcinomes séreuses (71/100), tandis que la plupart des
cancers du stroma des cordons sexuels étaient les tumeurs des
cellu |
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ISSN: | 1118-4841 |