Proceedings- Lactoferrin as a Marker of Systemic Inflammatory Response

Materials and methods. 51 patients, who were ill with generalized peritonitis, went through a prospective randomized research. They were randomized on groups depending on the objective score SAPS (1984): 29 survived people (53%) and 22 people with favorable end (47%). Intensive care and surgical tactics standardized patients. Lactoferrin (LF) as modulator of systemic inflammatory response (SIR) was assessed by immunoferment analysis. Statistical processing was done McNemar test. Results and discussion. In initial condition dynamics of this laboratory marker defined a group with favorable end as patients with granulocytes activation [1]. On the first 24 hours level of LF was marked twice above values of second group (95% confidence interval (CI) 1670-2024 ng/ml; p