Enzyme Activities and Histopathology of Selected Tissues in Rats Treated with Potassium bromate

The effect of chronic administration of potassium bromate (KBrO3), a flour improver, on some 'marker' enzymes of rat cellular system was investigated. The levels of these enzymes were measured progressively in the kidney, liver and small intestine, 24h after days 1, 3, 5, 10, 15 and 20 fol...

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Veröffentlicht in:African journal of biomedical research 2009-05, Vol.11 (1)
Hauptverfasser: Akanji, M. A, Nafiu, M. O, Yakubu, M. T
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Sprache:eng
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Zusammenfassung:The effect of chronic administration of potassium bromate (KBrO3), a flour improver, on some 'marker' enzymes of rat cellular system was investigated. The levels of these enzymes were measured progressively in the kidney, liver and small intestine, 24h after days 1, 3, 5, 10, 15 and 20 following the administration of 10mg/kg body weight of potassium bromate and when left for 10days without administration after their 20 daily doses. The alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and glutamate dehydrogenase (GDH) activities of all the tissues were significantly (P
ISSN:1119-5096