NEUROPHARMACOLOGICAL ACTIVITIES OF FICUS PLATYPHYLLA STEM BARK IN MICE

NEUROPHARMACOLOGICAL ACTIVITIES OF FICUS PLATYPHYLLA STEM BARK IN MICE

Methanol Extract Ficus platyphylla stem bark in dosages (17, 40 and 75, 150mg/kg) was found to produce a profound decrease in exploratory activity in mice, the extract indicated peripheral and central analgesic effects as shown by significant inhibition of acetic acid - induced writhing, and delayed...

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Veröffentlicht in:African journal of biomedical research 2004-05, Vol.7 (2)
1. Verfasser: WAKEEL O.K, P.I AZIBA, ASHOROBI R.B, UMUKORO, S, ADERIBIGBE A.0 AND AWE E.O
Format: Artikel
Sprache:eng
Schlagworte:
Neuropharmacology, Ficus platyphylla, stem bark, mice
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Zusammenfassung:Methanol Extract Ficus platyphylla stem bark in dosages (17, 40 and 75, 150mg/kg) was found to produce a profound decrease in exploratory activity in mice, the extract indicated peripheral and central analgesic effects as shown by significant inhibition of acetic acid - induced writhing, and delayed onset in leptazol induced-convulsion (seizures) in mice respectively. It also decreases the rate of leptazol induced mortality in mice. The totality of these effects showed that the extract possesses depressant action on the central nervous system.
ISSN:1119-5096