RELAXANT EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Cassia occidentials ON RAT AORTIC RINGS

RELAXANT EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Cassia occidentials ON RAT AORTIC RINGS

The relaxant effects of an aqueous extract of the leaf of plant cassia occidentalis (C.O.) were investigated in rat aortic rings with or without intact endothelium. The extract inhibited contraction elicited by noradrenaline (NA) and Potassium Chloride (KCI) dose dependently. It also relaxed aortic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:African journal of biomedical research 2005-03, Vol.4 (3)
1. Verfasser: AJAGBONNA O.P.. MOJIMINIYI F.B.O AND SOFOLA O.A
Format: Artikel
Sprache:eng
Schlagworte:
Cassia occidentials
Rat aorta
Vasodilatation, Vascular endothelium
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The relaxant effects of an aqueous extract of the leaf of plant cassia occidentalis (C.O.) were investigated in rat aortic rings with or without intact endothelium. The extract inhibited contraction elicited by noradrenaline (NA) and Potassium Chloride (KCI) dose dependently. It also relaxed aortic rings precontracted with 10-7 M NA and 50m M KCI. This relaxation did not require the presence of an intact vascular endothelium and was not affected by indomethacin (Prostacylin inhibitor) and methylene blue.
ISSN:1119-5096