A case control study of cardiovascular health in chemical war disabled Iranian victims
Background: Sulfur mustard (SM) is an alkylating chemical warfare agent that was widely used during Iran-Iraq war between 1983 and 1988. SM exposure leads to various late complications. The aim of this study was to determine the late cardiovascular effects of SM in war-disabled Iranian victims. Mate...
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Veröffentlicht in: | Indian journal of critical care medicine 2011-01, Vol.14 (3) |
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Sprache: | eng |
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Zusammenfassung: | Background: Sulfur mustard (SM) is an alkylating chemical warfare agent
that was widely used during Iran-Iraq war between 1983 and 1988. SM
exposure leads to various late complications. The aim of this study was
to determine the late cardiovascular effects of SM in war-disabled
Iranian victims. Materials and Methods: This was a retrospective cohort
case control study on 50 patients with symptoms of SM exposure and 50
cases who had been in Iran-Iraq war, without chemical injury. We
performed exercise stress test and echocardiography for all of
patients. Results: The study group comprised 100 males of mean age 45.6
± 6.2 years. In chemical war injury group, two patients (4%) had
positive exercise stress test. On coronary angiography, they were found
to have coronary artery disease. One patient had severe mitral
regurgitation and normal coronary angiography; he was referred for
mitral valve replacement. Left ventricular (LV) diastolic abnormality
was detected in 23% of these subjects. In another group, 5% had LV
diastolic abnormality (P = 0.02) and all of them had normal stress
test. Conclusions: Cardiovascular abnormalities are another late
complication in chemical war disabled Iranian victims. Diastolic
dysfunction was the most common abnormality in both groups of patients. |
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ISSN: | 0972-5229 |