Re and 99mTc complexes of BodP3 – multi-modality imaging probes

A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.

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Veröffentlicht in:Chemical Communications 2014-12, Vol.50, p.15503-15505
Hauptverfasser: Davies, Laura H., Kasten, Benjamin B., Benny, Paul D., Arrowsmith, R, Ge, Haobo, Pascu, Sofia, Botchway, Stan W., Clegg, William, Harrington, Ross W., Higham, Lee J.
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Sprache:eng
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Zusammenfassung:A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.
ISSN:1359-7345
1364-548X
DOI:10.1039/C4CC06367H