In Vitro and In Vivo Trypanocidal Effects of the Cyclopalladated Compound 7a, a Drug Candidate for Treatment of Chagas' Disease

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2010-08, Vol.54 (8), p.3318-3325
Hauptverfasser:	MATSUO, Alisson L, SILVA, Luis S, TORRECILHAS, Ana C, PASCOALINO, Bruno S, RAMOS, Thiago C, RODRIGUES, Elaine G, SCHENKMAN, Sergio, CAIRES, Antonio C. F, TRAVASSOS, Luiz R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cell Line Chagas Disease Chagas Disease - drug therapy Chagas Disease - mortality Chagas Disease - parasitology Chagas Disease - pathology Experimental Therapeutics Female Human protozoal diseases Humans Infectious diseases Medical sciences Mice Mice, Inbred BALB C Microscopy, Electron, Transmission Nitroimidazoles - administration & dosage Nitroimidazoles - chemistry Nitroimidazoles - pharmacology Nitroimidazoles - therapeutic use Palladium Palladium - administration & dosage Palladium - chemistry Palladium - pharmacology Palladium - therapeutic use Parasitic diseases Parasitic Sensitivity Tests Pharmacology. Drug treatments Protozoal diseases Treatment Outcome Trypanocidal Agents Trypanocidal Agents - administration & dosage Trypanocidal Agents - chemistry Trypanocidal Agents - pharmacology Trypanocidal Agents - therapeutic use Trypanosoma cruzi Trypanosoma cruzi - drug effects Trypanosoma cruzi - growth & development Trypanosoma cruzi - pathogenicity Trypanosoma cruzi - ultrastructure Trypanosomiasis
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.00323-10