Mechanism of Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase by a Stavudine Analogue, 4′-Ethynyl Stavudine Triphosphate

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2008-06, Vol.52 (6), p.2035-2042
Hauptverfasser:	Yang, Guangwei, Wang, Jimin, Cheng, Yao, Dutschman, Ginger E, Tanaka, Hiromichi, Baba, Masanori, Cheng, Yung-Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents Anti-HIV Agents - chemistry Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Base Sequence Biological and medical sciences Crystallization HIV Reverse Transcriptase HIV Reverse Transcriptase - antagonists & inhibitors HIV Reverse Transcriptase - chemistry HIV Reverse Transcriptase - metabolism HIV-1 HIV-1 - drug effects HIV-1 - enzymology HIV-1 - genetics Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Kinetics Medical sciences Models, Molecular Molecular Sequence Data Pharmacology. Drug treatments Polyphosphates Reverse Transcriptase Inhibitors - chemistry Reverse Transcriptase Inhibitors - pharmacology Stavudine Stavudine - analogs & derivatives Stavudine - chemistry Stavudine - pharmacology Structure-Activity Relationship Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.00083-08