MicroRNA: Perspectives in Health and Diseases

This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology. Chapter 1 Controlling the Biogenesis of the Smallest Regulators [Ketki Patne and Rohini Muthuswami] Chapter 2 Computational Analysis of miRNAs, Their Target Sequences and Their Role in Gene Regulatory Networks [Pamchui Muiwo, Priyatama Pandey, and Alok Bhattacharya] Chapter 3 miRNAs: Small RNAs with Big Regulatory Functions in Parasitic Diseases [Sneha Anand and Madhubala Rentala] Chapter 4 Role of miRNA in Multiple Sclerosis [Krishnaraj Thirugnanasambantham, Villianur Ibrahim Hairul Islam, Subramanian Saravanan, Venugopal Senthil Kumar, Ganapathy Ashok, and Muthiah Chellappandian] Chapter 5 miRNA Dysregulation in Inflammatory Bowel Disease and Its Consequences [Jaishree Paul and Swati Valmiki] Chapter 6 Involvement of MicroRNAs in Alzheimer’s Disease [Malay Bhattachayya and Sanghamitra Bandyopadhyay] Chapter 7 MicroRNAs in Neurogenesis and Neurodegeneration [Mayuresh A. Sarangdhar and Beena Pillai] Chapter 8 MicroRNAs in the Progression of Hepatocellular Carcinoma [Kishor Pant, Amit K. Mishra, and Senthil Kumar Venugopal] Chapter 9 MicroRNA Regulation of Invasive Phenotype of Glioblastoma [Omkar Vinchure and Ritu Kulshreshtha] Prof. Jaishree Paul is currently working as Scientist at Jawaharlal Lal Nehru University. She is currently involved in exploring and understanding the basic mechanisms of inflammatory bowel disease, particularly ulcerative colitis. She has more than 25 years of teaching experience and has published more than 50 research papers. She has solely authored a book entitled `Handbook of disease causing Microbes' published by Ane and CRC press and has contributed chapters in six books with Elsevier and with local publishers of repute. She has been invited as speaker at many international conferences. She has been awarded Visitor’s Research award by the President of India on 14th March, 2016. Dr. Rohini Muthuswami is currently working as Scientist at Jawaharlal Lal Nehru University. She is currently involved in knowing the epigenetic mechanisms that regulate the cellular processes. She has published 15 research papers and has written a book on `Exploring the Biological World' with National Book Trust, India and has also contributed a chapter on Chromatin Rem