Modern Avenues in Metal-Nucleic Acid Chemistry

Volume 25, entitled Modern Avenues in Metal-Nucleic Acid Chemistry , of the series Metal Ions in Life Sciences (MILS), provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches. It consists of 15 comprehensive chapters with over 1600 citations, 160 figures ( 90 of them in color), with key contributions from 40 international experts from Europe, Asia, and America. It is an essential resource for scientists from numerous disciplines, ranging from materials science to biochemistry, by way of classical chemistry and physics. • It offers an update on nucleic acid – metal complex bioconjugates and their applications • It provides an insight into coordination polymers involving nucleic acid components • It covers a wide range of nucleic acids, from DNA duplexes, triplexes and quadruplexes to RNA Chapter 1 Porous materials built up from metal-nucleobase materials Garikoitz Beobide, Oscar Castillo, Antonio Luque, and Sonia Pérez-Yáñez Chapter 2 Cytosine and its derivatives as useful tools to build unusual and fascinating architectures Teresa F. Mastropietro and Giovanni De Munno Chapter 3 Coordination polymers with nucleobase derivatives: from electronic nanodevices to sensors Noelia Maldonado and Pilar Amo-Ochoa Chapter 4 Heavy coinage metal nucleobase, nucleoside and (oligo)nucleotide systems: recent developments in self-assembly, opto-electronics and DNA integration Andrew Houlton Chapter 5 Interplay between non-covalent interactions and metal ions in nucleic acids and their constituents Miquel Barceló-Oliver, Antonio Frontera, Juan Jesús Fiol, Ángel García-Raso, and Ángel Terrón Chapter 6 Biological implications of metal-nucleobase complexes Saurabh Joshi, Ankita Jaiswal, Rajneesh Kumar Prajapati, and Sandeep Verma Chapter 7 Stimuli-responsive DNA-binding metal complexes Tim Ke