The Lack of Long Range Correlations is a Necessary Condition for a Functional Biologically Active Protein

J.Phys. A 1997, v.30, N 22, 7765-73 We study random heteropolymer chain with gaussian distribution of kinds of monomers. The long-range correlations between kinds of monomers were introduce. The mean-field analysis of such heteropolymer indicates the existence of infinite energetic barrier between h...

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Hauptverfasser:	Mamasakhlisov, E. Sh, Morozov, V. F, Shahinian, M. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Physics - Disordered Systems and Neural Networks Physics - Soft Condensed Matter Quantitative Biology - Biomolecules Quantitative Biology - Cell Behavior Quantitative Biology - Genomics Quantitative Biology - Molecular Networks Quantitative Biology - Neurons and Cognition Quantitative Biology - Other Quantitative Biology - Populations and Evolution Quantitative Biology - Quantitative Methods Quantitative Biology - Subcellular Processes Quantitative Biology - Tissues and Organs
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Zusammenfassung:	J.Phys. A 1997, v.30, N 22, 7765-73 We study random heteropolymer chain with gaussian distribution of kinds of monomers. The long-range correlations between kinds of monomers were introduce. The mean-field analysis of such heteropolymer indicates the existence of infinite energetic barrier between heteropolymer random coil and frozen states. Thus, the frozen state is kinetically unavailable for the random heteropolymer with power-law correlations in monomers' sequence. The relationship between our results and some early obtained results for the DNA intrones sequences are discussed.
DOI:	10.48550/arxiv.cond-mat/9802225