Primary Sequences of Protein-Like Copolymers: Levy Flight Type Long Range Correlations

Phys. Rev. E - Rapid Communication, v. 64, n. 10, 040903, 2001 We consider the statistical properties of primary sequences of two-letter HP copolymers (H for hydrophobic and P for polar) designed to have water soluble globular conformations with H monomers shielded from water inside the shell of P monomers. We show, both by computer simulations and by exact analytical calculation, that for large globules and flexible polymers such sequences exhibit long-range correlations which can be described by Levy-flight statistics.