Manifestation of aberrations in full-field optical coherence tomography

We report on a theoretical model for image formation in full-field optical coherence tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual confocal pinhole in FFOCT, its imaging performance is equivalent to a scanning time-gated coherent confocal microscope. In ag...

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Veröffentlicht in:arXiv.org 2021-07
Hauptverfasser: Barolle, Victor, Scholler, Jules, Mecê, Pedro, Chassot, Jean-Marie, Groux, Kassandra, Fink, Mathias, Boccara, A Claude, Aubry, Alexandre
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Sprache:eng
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Zusammenfassung:We report on a theoretical model for image formation in full-field optical coherence tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual confocal pinhole in FFOCT, its imaging performance is equivalent to a scanning time-gated coherent confocal microscope. In agreement with optical experiments enabling a precise control of aberrations, FFOCT is shown to have nearly twice the resolution of standard imaging at moderate aberration level. Beyond a rigorous study on the sensitivity of FFOCT with respect to aberrations, this theoretical model paves the way towards an optimized design of adaptive optics and \rev{computational tools} for high-resolution and deep imaging of biological tissues.
ISSN:2331-8422
DOI:10.48550/arxiv.2101.09996