Antibiotics Time Machine is NP-hard
The antibiotics time machine is an optimization question posed by Mira \latin{et al.} on the design of antibiotic treatment plans to minimize antibiotic resistance. The problem is a variation of the Markov decision process. These authors asked if the problem can be solved efficiently. In this paper,...
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creator | Tran, Ngoc Mai Yang, Jed |
description | The antibiotics time machine is an optimization question posed by Mira
\latin{et al.} on the design of antibiotic treatment plans to minimize
antibiotic resistance. The problem is a variation of the Markov decision
process. These authors asked if the problem can be solved efficiently. In this
paper, we show that this problem is NP-hard in general. |
doi_str_mv | 10.48550/arxiv.1505.02694 |
format | Article |
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\latin{et al.} on the design of antibiotic treatment plans to minimize
antibiotic resistance. The problem is a variation of the Markov decision
process. These authors asked if the problem can be solved efficiently. In this
paper, we show that this problem is NP-hard in general.</description><identifier>DOI: 10.48550/arxiv.1505.02694</identifier><language>eng</language><subject>Mathematics - Dynamical Systems ; Mathematics - Optimization and Control ; Quantitative Biology - Populations and Evolution</subject><creationdate>2015-05</creationdate><rights>http://arxiv.org/licenses/nonexclusive-distrib/1.0</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>228,230,780,885</link.rule.ids><linktorsrc>$$Uhttps://arxiv.org/abs/1505.02694$$EView_record_in_Cornell_University$$FView_record_in_$$GCornell_University$$Hfree_for_read</linktorsrc><backlink>$$Uhttps://doi.org/10.48550/arXiv.1505.02694$$DView paper in arXiv$$Hfree_for_read</backlink></links><search><creatorcontrib>Tran, Ngoc Mai</creatorcontrib><creatorcontrib>Yang, Jed</creatorcontrib><title>Antibiotics Time Machine is NP-hard</title><description>The antibiotics time machine is an optimization question posed by Mira
\latin{et al.} on the design of antibiotic treatment plans to minimize
antibiotic resistance. The problem is a variation of the Markov decision
process. These authors asked if the problem can be solved efficiently. In this
paper, we show that this problem is NP-hard in general.</description><subject>Mathematics - Dynamical Systems</subject><subject>Mathematics - Optimization and Control</subject><subject>Quantitative Biology - Populations and Evolution</subject><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>GOX</sourceid><recordid>eNotzrsKwjAUgOEsDqI-gJMF59YkPUmTsYg3qJehezlJUwxYlVRE316sTv_28xEyZTQBJQRdYHj5Z8IEFQnlUsOQzPPrwxt_e3jbRaVvXbRHe_ZXF_kuOpziM4Z6TAYNXjo3-XdEyvWqXG7j4rjZLfMiRplBXIPjyhjpOE2RUs0ablHbmoJkSqMCEEJIljUqzYwBZq3mHIUGlynDmjodkdlv2yure_Athnf11Va9Nv0A6GY3zw</recordid><startdate>20150511</startdate><enddate>20150511</enddate><creator>Tran, Ngoc Mai</creator><creator>Yang, Jed</creator><scope>AKZ</scope><scope>ALC</scope><scope>GOX</scope></search><sort><creationdate>20150511</creationdate><title>Antibiotics Time Machine is NP-hard</title><author>Tran, Ngoc Mai ; Yang, Jed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a674-d4e28bb6e203a0091f2ca9cd046189a844555617f837bb41cc922a594e78b1fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Mathematics - Dynamical Systems</topic><topic>Mathematics - Optimization and Control</topic><topic>Quantitative Biology - Populations and Evolution</topic><toplevel>online_resources</toplevel><creatorcontrib>Tran, Ngoc Mai</creatorcontrib><creatorcontrib>Yang, Jed</creatorcontrib><collection>arXiv Mathematics</collection><collection>arXiv Quantitative Biology</collection><collection>arXiv.org</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Tran, Ngoc Mai</au><au>Yang, Jed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibiotics Time Machine is NP-hard</atitle><date>2015-05-11</date><risdate>2015</risdate><abstract>The antibiotics time machine is an optimization question posed by Mira
\latin{et al.} on the design of antibiotic treatment plans to minimize
antibiotic resistance. The problem is a variation of the Markov decision
process. These authors asked if the problem can be solved efficiently. In this
paper, we show that this problem is NP-hard in general.</abstract><doi>10.48550/arxiv.1505.02694</doi><oa>free_for_read</oa></addata></record> |
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subjects | Mathematics - Dynamical Systems Mathematics - Optimization and Control Quantitative Biology - Populations and Evolution |
title | Antibiotics Time Machine is NP-hard |
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