Antibiotics Time Machine is NP-hard

The antibiotics time machine is an optimization question posed by Mira \latin{et al.} on the design of antibiotic treatment plans to minimize antibiotic resistance. The problem is a variation of the Markov decision process. These authors asked if the problem can be solved efficiently. In this paper,...

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Hauptverfasser: Tran, Ngoc Mai, Yang, Jed
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Sprache:eng
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Zusammenfassung:The antibiotics time machine is an optimization question posed by Mira \latin{et al.} on the design of antibiotic treatment plans to minimize antibiotic resistance. The problem is a variation of the Markov decision process. These authors asked if the problem can be solved efficiently. In this paper, we show that this problem is NP-hard in general.
DOI:10.48550/arxiv.1505.02694