BF2‑Oxasmaragdyrin Nanoparticles: A Non-toxic, Photostable, Enhanced Non-radiative Decay-Assisted Efficient Photothermal Cancer Theragnostic Agent

Photothermal therapy (PTT), a simple and minimally invasive procedure, is an attractive option for cancer therapy. To date, inorganic agents have been widely employed as photothermal agents; however, organic molecules may provide a solution to rapid metabolic/in vivo clearance. Herein, we prepared l...

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Veröffentlicht in:ACS applied materials & interfaces 2020-11, Vol.12 (47), p.52329-52342
Hauptverfasser: Laxman, Kandala, Reddy, B. Pradeep K, Mishra, Sumit K, Gopal, Maddala Bala, Robinson, Andrea, De, Abhijit, Srivastava, Rohit, Ravikanth, Mangalampalli
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Sprache:eng
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Zusammenfassung:Photothermal therapy (PTT), a simple and minimally invasive procedure, is an attractive option for cancer therapy. To date, inorganic agents have been widely employed as photothermal agents; however, organic molecules may provide a solution to rapid metabolic/in vivo clearance. Herein, we prepared lipid (S 75)-stabilized meso-tritolyl-BF2-oxasmaragdyrin nanoparticles (TBSNPs) using thin-film hydration and homogenization. Assessment of the physicochemical properties of the TBSNPs reveals the formation of particles of size
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.0c13326