Personalized drug screening for functional tumor profiling
Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements obse...
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| Hauptverfasser: | , , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Cambridge University Press
2022
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| Schriftenreihe: | Elements in Molecular Oncology
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| Schlagworte: | |
| Online-Zugang: | DE-12 DE-473 URL des Erstveröffentlichers |
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| 100 | 1 | |a El-Khoury, Victoria |d 1977- |0 (DE-588)1264159633 |4 aut | |
| 245 | 1 | 0 | |a Personalized drug screening for functional tumor profiling |c Victoria El-Khoury, Tatiana Michel, Hichul Kim, Yong-Jun Kwon |
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| 520 | |a Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology | ||
| 650 | 4 | |a Cancer / Chemotherapy | |
| 650 | 4 | |a Personalized medicine | |
| 650 | 4 | |a Antineoplastic agents | |
| 700 | 1 | |a Michel, Tatiana |d 1975- |0 (DE-588)1264160062 |4 aut | |
| 700 | 1 | |a Kim, Hichul |d 1976- |0 (DE-588)1264160437 |4 aut | |
| 700 | 1 | |a Kwon, Yong-Jun |d 1976- |0 (DE-588)1264160739 |4 aut | |
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Datensatz im Suchindex
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| DE-BY-UBG_local_url | Verlag https://doi.org/10.1017/9781009037877 |
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| author | El-Khoury, Victoria 1977- Michel, Tatiana 1975- Kim, Hichul 1976- Kwon, Yong-Jun 1976- |
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| author_facet | El-Khoury, Victoria 1977- Michel, Tatiana 1975- Kim, Hichul 1976- Kwon, Yong-Jun 1976- |
| author_role | aut aut aut aut |
| author_sort | El-Khoury, Victoria 1977- |
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| dewey-full | 616.994061 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.994061 |
| dewey-search | 616.994061 |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| doi_str_mv | 10.1017/9781009037877 |
| format | Electronic eBook |
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| id | DE-604.BV048388165 |
| illustrated | Not Illustrated |
| index_date | 2024-09-19T15:57:26Z |
| indexdate | 2024-09-27T17:03:59Z |
| institution | BVB |
| isbn | 9781009037877 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-033766920 |
| oclc_num | 1339077616 |
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| owner | DE-12 DE-473 DE-BY-UBG |
| owner_facet | DE-12 DE-473 DE-BY-UBG |
| physical | 1 Online-Ressource (22 Seiten) |
| psigel | ZDB-20-CBO ZDB-20-CBO BSB_PDA_CBO ZDB-20-CBO UBG_PDA_CBO |
| publishDate | 2022 |
| publishDateSearch | 2022 |
| publishDateSort | 2022 |
| publisher | Cambridge University Press |
| record_format | marc |
| series2 | Elements in Molecular Oncology |
| spellingShingle | El-Khoury, Victoria 1977- Michel, Tatiana 1975- Kim, Hichul 1976- Kwon, Yong-Jun 1976- Personalized drug screening for functional tumor profiling Cancer / Chemotherapy Personalized medicine Antineoplastic agents |
| title | Personalized drug screening for functional tumor profiling |
| title_auth | Personalized drug screening for functional tumor profiling |
| title_exact_search | Personalized drug screening for functional tumor profiling |
| title_exact_search_txtP | Personalized drug screening for functional tumor profiling |
| title_full | Personalized drug screening for functional tumor profiling Victoria El-Khoury, Tatiana Michel, Hichul Kim, Yong-Jun Kwon |
| title_fullStr | Personalized drug screening for functional tumor profiling Victoria El-Khoury, Tatiana Michel, Hichul Kim, Yong-Jun Kwon |
| title_full_unstemmed | Personalized drug screening for functional tumor profiling Victoria El-Khoury, Tatiana Michel, Hichul Kim, Yong-Jun Kwon |
| title_short | Personalized drug screening for functional tumor profiling |
| title_sort | personalized drug screening for functional tumor profiling |
| topic | Cancer / Chemotherapy Personalized medicine Antineoplastic agents |
| topic_facet | Cancer / Chemotherapy Personalized medicine Antineoplastic agents |
| url | https://doi.org/10.1017/9781009037877 |
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