Adverse Outcome Pathway on chronic binding of antagonist to N-methyl-D-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities
It is well documented and accepted that learning and memory processes rely on physiological functioning of the glutamate receptor N-methyl-D-aspartate (NMDAR). Both animal and human studies investigating NMDA itself, experiments with NMDAR antagonists and mutant mice lacking NMDAR subunits strongly...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
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Paris
OECD Publishing
2016
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| Schriftenreihe: | OECD Series on Adverse Outcome Pathways
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| Online-Zugang: | kostenfrei |
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