Next generation sequencing and data analysis

This textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications. The reader learns how to perform Next Generation Sequencing data analysis, how to interpret and visualize the data, and acquires knowledge on the statis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Weitere Verfasser: Kappelmann-Fenzl, Melanie (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Cham, Switzerland Springer [2021]
Schriftenreihe:Learning materials in biosciences
Schlagworte:
Online-Zugang:DE-1050
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Inhaltsangabe:
  • Chapter 1. Next Generation Sequencing (NGS)- What can be sequenced?
  • Opportunities and Perspectives of NGS Applications in Cancer Research
  • Chapter 3. Library Construction for NGS
  • Chapter 4. NGS Technologies
  • Chapter 5. Computer Setup
  • Chapter 6. Introduction to Command Line
  • Chapter 7. NGS Data
  • Chapter 8. Reference Genome
  • Chapter 9. Alignment
  • Chapter 10. Identification of Genetic Variants and de novo Mutations Based on NGS
  • Chapter 11. Design and Analysis of RNA Sequencing Data
  • Chapter 12. Design and Analysis of Epigenetics and ChIP-Sequencing Data
  • APPENDIX.