SUMOylation and ubiquitination current and emerging concepts
Most proteins undergo post-translational modifications altering physical and chemical properties, folding, conformation distribution, stability, activity and function. Ubiquitin and SUMOs are related small proteins that are members of the large ubiquitin superfamily of post-translational modifiers....
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Norfolk, UK
Caister Academic Press
[2019]
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| 245 | 1 | 0 | |a SUMOylation and ubiquitination |b current and emerging concepts |c edited by Van G. Wilson, Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M University, Bryan, TX, USA |
| 264 | 1 | |a Norfolk, UK |b Caister Academic Press |c [2019] | |
| 300 | |a viii, 503 Seiten |b Illustrationen | ||
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| 520 | 3 | |a Most proteins undergo post-translational modifications altering physical and chemical properties, folding, conformation distribution, stability, activity and function. Ubiquitin and SUMOs are related small proteins that are members of the large ubiquitin superfamily of post-translational modifiers. Written by highly respected leaders in their fields under the expert guidance of the editor, this volume covers the principles of ubiquitination and SUMOylation, presents detailed reviews of current and emerging concepts and highlights new advances in all areas of SUMOylation and ubiquitination. Topics of note include: the ubiquitin superfamily, the ubiquitin toolbox, onco viral exploitation of the SUMO system, small molecule modulators of desumoylation, mass spectrometry, global proteomic profiling of SUMO and ubiquitin, biotin-based approaches, genetic screening, SUMOylation networks in humans, targets for ubiquitin ligases, regulation of p53, protein homeostasis, miRNAs, DNA replication, DNA damage response, telomere biology, intracellular trafficking, regulation of angiogenesis, brain ischemia, autophagy, assembly and activity, antiviral defense, HIV infection, amyloid and amyloid-like proteins, plant immunity. This comprehensive and up-to-date book is the definitive reference volume on all aspects of SUMOylation and ubiquitination and is an essential acquisition for anyone involved in this area of biology | |
| 653 | 0 | |a Ubiquitin | |
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| 653 | 0 | |a Post-translational modification | |
| 653 | 0 | |a Ubiquitin | |
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Datensatz im Suchindex
| _version_ | 1819767327641567232 |
|---|---|
| adam_text | Contents Part I General Principles 1 The Rise of the Ubiquitin Super Family 1 3 Van G. Wilson 2 Cracking the Ubiquitin Code: The Ubiquitin Toolbox 15 Monique P.C. Mulder, Katharina F. Witting and Huib Ovaa 3 Recent Highlights: Onco Viral Exploitation of the SUMO System 35 Domenico Mattoscio, Alessandro Medda and Susanna Chiocca 4 Progress in the Discovery of Small Molecule Modulators of DeSUMOylation 51 Shiyao Chen, Duoling Dong, Weixiang Xin and Huchen Zhou Part II Novel and Advancing Technologies 5 Identification of SUMOylated and Ubiquitinated Substrates by Mass Spectrometry 69 71 Francis P. McManus and Pierre Thibault 6 Global Proteomic Profiling of SUMO and Ubiquitin 95 Alla Ahmad, Ryan Lumpkin and Elizabeth A. Komives 7 Biotin-based Approaches for the Study of Ubiquitin and Ubiquitinlike Protein Modifications 101 James D. Sutherland, Orhi Barroso-Gomila and Rosa Barrio 8 Screening Mammalian SUMOylated Proteins by Fluorescence Protein Reconstitution 123 Maki Komiya, Mizukl Endo and Takeaki Ozawa 9 Dissecting Complex SUMOylation Networks in Humans 135 Ijeoma Uzomaand Heng Zhu 10 TULIP: Targets of Ubiquitin Ligases Identified by Proteomics Román González-Prieto and Alfred C.O. Vertegaal 147
iv I Contents Part III Cellular Processes 11 Regulation of p53 Family Members by the Ubiquitin and SUMO Modification Systems 161 163 Viola Calabro and Maria Vivo 12 Interplay between the Ubiquitin Proteasome System and Mitochondria for Protein Homeostasis 193 Mafalda Escobar-Henriques, Selver Altin and Fabian den Brave 13 Interplay of Ubiquitination and SUMOylation with míRNAs 217 Yashika Agrawal and Manas Kumar Santra 14 The Role of Ubiquitination and SUMOylation in DNA Replication 231 Tarek Abbas 15 Roles of Ubiquitination and SUMOylation in DNA Damage Response 263 Siyuan Su, Yanqiong Zhang and Pengda Liu 16 The Role of Ubiquitination and SUMOylation in Telomere Biology 289 Michal Zalzman, W. Alex Meitzer, Benjamin A. Portney, Robert A. Brown and Aditi Gupta 17 Role of Ubiquitin and SUMO in Intracellular Trafficking 303 Maria Sundvall 18 Roles of Ubiquitination and SUMOylation in the Regulation of Angiogenesis 313 Andrea Rabellino, Cristina Andreani and Pier Paolo Scaglioni 19 The Role of SUMOylation and Ubiquitination in Brain Ischaemia: Critical Concepts and Clinical Implications 331 Joshua D. Bernstock, Daniel G. Ye, Dagoberto Estevez, Gustavo Chagoya, Ya-Chao Wang, Florian Gessler, John M. Hallenbeck and Wei Yang 20 The Role of Ubiquitination and SUMOylation in Autophagy 349 Sushil Devkota 21 Ubiquitin and SUMO Modifications in Caenorhabditis elegans Stress Response 363 Krzysztof Drabikowski Part IV Infection, Immunity and Disease 22 Beyond Degradation: Ubiquitination of the Inflammasome Regulates Assembly and Activity 377 379 Joseph S. Bednash and Rama K. Mallampalli
23 Ubiquitin and SUMO in Antiviral Defence 389 Van G. Wilson 24 Ubiquitination and SUMOylation in HIV Infection: Friends and Foes Marta Colomer-Lluch, Sergio Castro-Gonzalez and Ruth Serra-Moreno 417
·,-■ ·■ 25 Ubiquitination and SUMOylation of Amyloid and Amyloid-like Proteins in Health and Disease 453 Lenzie Ford, Luana Fioriti and Eric R. Kandel 26 Keeping Up with the Pathogens: The Role of SUMOylation in Plant Immunity 489 Rebecca Morrell and Ari Sadanandom Index 501 v
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| id | DE-604.BV047036888 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T08:34:29Z |
| institution | BVB |
| isbn | 9781912530120 1912530120 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032444038 |
| oclc_num | 1235890412 |
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| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | viii, 503 Seiten Illustrationen |
| publishDate | 2019 |
| publishDateSearch | 2019 |
| publishDateSort | 2019 |
| publisher | Caister Academic Press |
| record_format | marc |
| spellingShingle | Wilson, Van G. SUMOylation and ubiquitination current and emerging concepts |
| title | SUMOylation and ubiquitination current and emerging concepts |
| title_auth | SUMOylation and ubiquitination current and emerging concepts |
| title_exact_search | SUMOylation and ubiquitination current and emerging concepts |
| title_full | SUMOylation and ubiquitination current and emerging concepts edited by Van G. Wilson, Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M University, Bryan, TX, USA |
| title_fullStr | SUMOylation and ubiquitination current and emerging concepts edited by Van G. Wilson, Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M University, Bryan, TX, USA |
| title_full_unstemmed | SUMOylation and ubiquitination current and emerging concepts edited by Van G. Wilson, Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M University, Bryan, TX, USA |
| title_short | SUMOylation and ubiquitination |
| title_sort | sumoylation and ubiquitination current and emerging concepts |
| title_sub | current and emerging concepts |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032444038&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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