Immunology and Evolution of Infectious Disease
From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecolo...
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| Sprache: | English |
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Princeton, NJ
Princeton University Press
[2020]
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| 520 | |a From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine.The author uses an evolutionary perspective to meld the terms and findings of molecular biology, immunology, pathogen biology, and population dynamics. This multidisciplinary approach offers newcomers a readable introduction while giving specialists an invaluable guide to allied subjects. Every aspect of the immune response is presented in the functional context of parasite recognition and defense--an emphasis that gives structure to a tremendous amount of data and brings into sharp focus the great complexity of immunology. The problems that end each chapter set the challenge for future research, and the text includes extensive discussion of HIV, influenza, foot-and-mouth disease, and many other pathogens.This is the only book that treats in an integrated way all factors affecting variation in infectious disease. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For molecular biologists, immunologists, and evolutionary biologists, this book provides new insight into infectious agents, immunity, and the evolution of infectious disease | ||
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| 650 | 4 | |a immunodominance | |
| 650 | 4 | |a mixotope | |
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| 650 | 4 | |a persistent infection | |
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Datensatz im Suchindex
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| author | Frank, Steven A. |
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616.9/0479 |
| dewey-search | 616.9/0479 |
| dewey-sort | 3616.9 3479 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1515/9780691220161 |
| format | Electronic eBook |
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| id | DE-604.BV046992896 |
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| indexdate | 2024-12-24T08:32:15Z |
| institution | BVB |
| isbn | 9780691220161 |
| language | English |
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| spelling | Frank, Steven A. Verfasser aut Immunology and Evolution of Infectious Disease Steven A. Frank Princeton, NJ Princeton University Press [2020] © 2002 1 online resource (360 pages) 40 line illus txt rdacontent c rdamedia cr rdacarrier Description based on online resource; title from PDF title page (publisher's Web site, viewed 28. Okt 2020) From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine.The author uses an evolutionary perspective to meld the terms and findings of molecular biology, immunology, pathogen biology, and population dynamics. This multidisciplinary approach offers newcomers a readable introduction while giving specialists an invaluable guide to allied subjects. Every aspect of the immune response is presented in the functional context of parasite recognition and defense--an emphasis that gives structure to a tremendous amount of data and brings into sharp focus the great complexity of immunology. The problems that end each chapter set the challenge for future research, and the text includes extensive discussion of HIV, influenza, foot-and-mouth disease, and many other pathogens.This is the only book that treats in an integrated way all factors affecting variation in infectious disease. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For molecular biologists, immunologists, and evolutionary biologists, this book provides new insight into infectious agents, immunity, and the evolution of infectious disease In English Epstein-Barr virus IgG. Listeria monocytogenes MHC polymorphism Neurospora crassa Salmonella enterica West Nile virus affinity maturation;antibody binding antibodies antigenic variation archival library of variants cross-reactivity cytopathic versus noncytopathic dengue virus dosage equilibrium affinity experimental evolution fimbriae generative mechanisms geographic scale helper T cells heparan sulfate (HS) immune regulation immunodominance mixotope murine leukemia virus persistent infection population size rotavirus yellow fever virus MEDICAL / Immunology bisacsh Antigens Host-parasite relationships Genetic aspects Immunogenetics Microorganisms Evolution Molecular evolution Parasite antigens Variation https://doi.org/10.1515/9780691220161 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Frank, Steven A. Immunology and Evolution of Infectious Disease Epstein-Barr virus IgG. Listeria monocytogenes MHC polymorphism Neurospora crassa Salmonella enterica West Nile virus affinity maturation;antibody binding antibodies antigenic variation archival library of variants cross-reactivity cytopathic versus noncytopathic dengue virus dosage equilibrium affinity experimental evolution fimbriae generative mechanisms geographic scale helper T cells heparan sulfate (HS) immune regulation immunodominance mixotope murine leukemia virus persistent infection population size rotavirus yellow fever virus MEDICAL / Immunology bisacsh Antigens Host-parasite relationships Genetic aspects Immunogenetics Microorganisms Evolution Molecular evolution Parasite antigens Variation |
| title | Immunology and Evolution of Infectious Disease |
| title_auth | Immunology and Evolution of Infectious Disease |
| title_exact_search | Immunology and Evolution of Infectious Disease |
| title_full | Immunology and Evolution of Infectious Disease Steven A. Frank |
| title_fullStr | Immunology and Evolution of Infectious Disease Steven A. Frank |
| title_full_unstemmed | Immunology and Evolution of Infectious Disease Steven A. Frank |
| title_short | Immunology and Evolution of Infectious Disease |
| title_sort | immunology and evolution of infectious disease |
| topic | Epstein-Barr virus IgG. Listeria monocytogenes MHC polymorphism Neurospora crassa Salmonella enterica West Nile virus affinity maturation;antibody binding antibodies antigenic variation archival library of variants cross-reactivity cytopathic versus noncytopathic dengue virus dosage equilibrium affinity experimental evolution fimbriae generative mechanisms geographic scale helper T cells heparan sulfate (HS) immune regulation immunodominance mixotope murine leukemia virus persistent infection population size rotavirus yellow fever virus MEDICAL / Immunology bisacsh Antigens Host-parasite relationships Genetic aspects Immunogenetics Microorganisms Evolution Molecular evolution Parasite antigens Variation |
| topic_facet | Epstein-Barr virus IgG. Listeria monocytogenes MHC polymorphism Neurospora crassa Salmonella enterica West Nile virus affinity maturation;antibody binding antibodies antigenic variation archival library of variants cross-reactivity cytopathic versus noncytopathic dengue virus dosage equilibrium affinity experimental evolution fimbriae generative mechanisms geographic scale helper T cells heparan sulfate (HS) immune regulation immunodominance mixotope murine leukemia virus persistent infection population size rotavirus yellow fever virus MEDICAL / Immunology Antigens Host-parasite relationships Genetic aspects Immunogenetics Microorganisms Evolution Molecular evolution Parasite antigens Variation |
| url | https://doi.org/10.1515/9780691220161 |
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