Particle enhanced point of care diagnostics utilizing quartz crystal microbalances
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Düren
Shaker Verlag
2019
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| Schriftenreihe: | Schriftenreihe Mikrotechnik
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| Online-Zugang: | Inhaltsverzeichnis Inhaltsverzeichnis |
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| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV046231911 | ||
| 003 | DE-604 | ||
| 005 | 20191213 | ||
| 007 | t| | ||
| 008 | 191105s2019 gw a||| m||| 00||| eng d | ||
| 015 | |a 19,A40 |2 dnb | ||
| 015 | |a 19,H10 |2 dnb | ||
| 016 | 7 | |a 1188836641 |2 DE-101 | |
| 020 | |a 9783844068122 |c Broschur : EUR 48.80 (DE), EUR 48.80 (AT), CHF 61.10 (freier Preis) |9 978-3-8440-6812-2 | ||
| 020 | |a 3844068120 |9 3-8440-6812-0 | ||
| 024 | 3 | |a 9783844068122 | |
| 035 | |a (OCoLC)1135391813 | ||
| 035 | |a (DE-599)DNB1188836641 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 044 | |a gw |c XA-DE-NW | ||
| 049 | |a DE-83 | ||
| 082 | 0 | |a 681.757 |2 23/ger | |
| 084 | |a ZN 3750 |0 (DE-625)157334: |2 rvk | ||
| 100 | 1 | |a Thies, Jan-Wilhelm |d 1985- |e Verfasser |0 (DE-588)1157036082 |4 aut | |
| 245 | 1 | 0 | |a Particle enhanced point of care diagnostics utilizing quartz crystal microbalances |c Jan-Wilhelm Thies |
| 264 | 1 | |a Düren |b Shaker Verlag |c 2019 | |
| 300 | |a 148 Seiten |b Illustrationen, Diagramme |c 21 cm, 245 g | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Schriftenreihe Mikrotechnik | |
| 502 | |b Dissertation |c Technische Universität Carolo-Wilhelmina zu Braunschweig |d 2019 | ||
| 650 | 0 | 7 | |a Mikrowaage |0 (DE-588)4169866-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Superparamagnetismus |0 (DE-588)4608043-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Nanopartikel |0 (DE-588)4333369-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Lab on a Chip |0 (DE-588)7610677-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Schwingquarz |0 (DE-588)4180559-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Empfindlichkeit |0 (DE-588)4127339-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Geräteentwicklung |0 (DE-588)4267986-2 |2 gnd |9 rswk-swf |
| 653 | |a Paperback / softback | ||
| 653 | |a Fachpublikum/ Wissenschaft | ||
| 653 | |a )Unsewn / adhesive bound | ||
| 653 | |a Oscillation circuit | ||
| 653 | |a magnetic manipulation | ||
| 653 | |a sensitivity enhancement | ||
| 653 | |a 1682: Hardcover, Softcover / Technik/Maschinenbau, Fertigungstechnik | ||
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
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| 689 | 0 | 1 | |a Mikrowaage |0 (DE-588)4169866-6 |D s |
| 689 | 0 | 2 | |a Schwingquarz |0 (DE-588)4180559-8 |D s |
| 689 | 0 | 3 | |a Empfindlichkeit |0 (DE-588)4127339-4 |D s |
| 689 | 0 | 4 | |a Nanopartikel |0 (DE-588)4333369-2 |D s |
| 689 | 0 | 5 | |a Superparamagnetismus |0 (DE-588)4608043-0 |D s |
| 689 | 0 | 6 | |a Geräteentwicklung |0 (DE-588)4267986-2 |D s |
| 689 | 0 | |5 DE-604 | |
| 856 | 4 | 2 | |m B:DE-101 |q application/pdf |u https://d-nb.info/1188836641/04 |3 Inhaltsverzeichnis |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031610390&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-031610390 | |
Datensatz im Suchindex
| _version_ | 1819771984410574848 |
|---|---|
| adam_text | CONTENTS
1
INTRODUCTION
.......................................................................................
1
2
MAGNETIC
MANIPULATION
&
MICROFLUIDICS
.............................................
3
2.1
THEORETICAL
BACKGROUND
&
STATE
OF
THE
ART
...................................
4
2.1.1
MAGNETIC
FIELD
......................................................................
4
2.1.2
FERROMAGNETISM
...................................................................
6
2.1.3
SUPERPARAMAGNETISM
............................................................
8
2.1.4
MANIPULATION
FORCES
............................................................
11
2.2
SIMULATION
OF
MAGNETIC
GUIDING
STRUCTURES
.................................
19
2.3
FABRICATION
.................................................................................
29
2.3.1
POLE
PIECE
FABRICATION
BY
ELECTROPLATING
..............................
29
2.3.2
FABRICATION
BASED
ON
FEMTOSECOND
LASER
ABLATION
..............
33
2.4
MAGNETIC
MANIPULATION
EXPERIMENTS
..........................................
35
3
QUARTZ
CRYSTAL
MICROBALANCE
............................................................
40
3.1
QCM
-
WORKING
PRINCIPLE
&
THEORETICAL
BACKGROUND
...................
41
3.1.1
QCM
MEASUREMENTS
IN
LIQUIDS
............................................
43
3.1.2
ELECTRICAL
EQUIVALENT
CIRCUIT
.................................................
45
3.1.3
QUALITY
FACTOR
.....................................................................
49
3.2
FLOW
CELL
DESIGN
CONSIDERATIONS
..................................................
50
3.2.1
FLUIDIC
DEMANDS/REQUIREMENTS
...........................................
50
3.2.2
MATERIAL
SELECTION
&
FABRICATION
DEMANDS
.........................
56
3.3
QCM
FABRICATION
PROCESS
............................................................
56
3.3.1
MICROFABRICATION
OF
THE
QCM
OSCILLATOR
..............................
57
3.3.2
FABRICATION
OF
SU-8
PHOTORESIST
MOULDS
.............................
59
CONTENTS
3.3.3
ROMS
FLOW
CELL
FABRICATION
..................................................
61
3.3.4
QCM
SENSOR
ASSEMBLY.........................................................
63
3.4
QCM
AS
BIOSENSOR
-
STATE
OF
THE
ART
................................................
65
3.4.1
SELF-ASSEMBLED-MONOLAYER
.................................................
66
3.4.2
DETECTION
ANTIBODIES,
FRAGMENTS
AND
ANTIBODY
SANDWICH
..
67
3.4.3
C-REACTIVE
PROTEIN
...............................................................
72
3.4.4
BLOCKING
OF
FREE
SURFACE
WITH
BSA
.......................................
73
4
QCM
MEASUREMENTS
........................................................................
74
4.1
Q-FACTOR
DETERMINATION
...............................................................
75
4.1.1
QCM
DAMPING
IN
LIQUIDS
......................................................
79
4.2
OSCILLATION
CIRCUITS
.......................................................................
82
4.2.1
PIERCE
OSCILLATOR
-
A
STATE
OF
THE
ART
CIRCUIT
.........................
82
4.2.2
PIERCE
OSCILLATOR
FEASIBILITY
TESTS
..........................................
83
4.2.3
NEW
OSCILLATOR
CIRCUIT
..........................................................
86
4.3
MEASUREMENT
SET
UP
..................................................................
90
4.4
QCM
MEASUREMENT
OF
CRP
SAMPLES
...........................................
92
5
EXTENDING
THE
MEASUREMENT
RANGE
/
SENSITIVITY
ENHANCEMENT
.......
96
5.1
MEASUREMENT
RANGE
EXTENSION
-
STATE
OF
THE
ART
.......................
97
5.1.1
ELISA
...................................................................................
98
5.1.2
ADOPTION
OF
THE
SANDWICH
ASSAY
PRINCIPLE
..........................
99
5.2
SANDWICH
ENHANCED
QCM
MEASUREMENTS
................................
101
5.3
COMPARISON
OF
THE
SANDWICH
TYPES
...........................................
110
6
ADVANCED
POC
SENSOR
CONCEPT
........................................................
115
6.1
COMBINATION
APPROACH
AND
BENEFITS
..............................................
116
CONTENTS
6.2
POTENTIAL
SCOPE
OF
APPLICATION
..................................................
116
6.3
THOUGHTS
ON
MATERIAL
SELECTION
AND
FABRICATION
.......................
119
6.4
PARTICLE
SELECTION
.......................................................................
120
7
SUMMARY
&
OUTLOOK
........................................................................
122
7.1
SUMMARY
..................................................................................
122
7.2
OUTLOOK
....................................................................................
124
8
LITERATURE
........................................................................................
126
8.1
JOURNAL
ARTICLES
ORIGINATING
FROM
THIS
WORK
...............................
127
8.2
SUPERVISED
STUDENTS
WORK
.........................................................
128
8.3
CITED
LITERATURE
..........................................................................
130
9
APPENDIX
........................................................................................
139
9.1
ELECTROPLATED
POLE
PIECES
ON
GLASS
CARRIER
................................
140
9.2
SU-8
MASTER
ON
GLASS
CARRIER
.....................................................
142
9.3
SU-8
MASTER
FOR
QCM
MEMBRANE
HOLDER
.................................
143
9.4
MASTER
FOR
QCM
SAMPLE
CHANNEL
..............................................
144
9.5
PDMS
SOFT
LITHOGRAPHY
..............................................................
145
9.6
QCM
QUARTZ
MEMBRANE
STRUCTURING
..........................................
146
9.7
LASERED
GLASS
CHANNEL
PREPARATION
&
BONDING
..........................
148
9.8
FS-LASER
PROCESS
PARAMETERS
......................................................
149
|
| any_adam_object | 1 |
| author | Thies, Jan-Wilhelm 1985- |
| author_GND | (DE-588)1157036082 |
| author_facet | Thies, Jan-Wilhelm 1985- |
| author_role | aut |
| author_sort | Thies, Jan-Wilhelm 1985- |
| author_variant | j w t jwt |
| building | Verbundindex |
| bvnumber | BV046231911 |
| classification_rvk | ZN 3750 |
| ctrlnum | (OCoLC)1135391813 (DE-599)DNB1188836641 |
| dewey-full | 681.757 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 681 - Precision instruments and other devices |
| dewey-raw | 681.757 |
| dewey-search | 681.757 |
| dewey-sort | 3681.757 |
| dewey-tens | 680 - Manufacture of products for specific uses |
| discipline | Handwerk und Gewerbe / Verschiedene Technologien Elektrotechnik / Elektronik / Nachrichtentechnik |
| format | Thesis Book |
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| genre | (DE-588)4113937-9 Hochschulschrift gnd-content |
| genre_facet | Hochschulschrift |
| id | DE-604.BV046231911 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T07:51:16Z |
| institution | BVB |
| isbn | 9783844068122 3844068120 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031610390 |
| oclc_num | 1135391813 |
| open_access_boolean | |
| owner | DE-83 |
| owner_facet | DE-83 |
| physical | 148 Seiten Illustrationen, Diagramme 21 cm, 245 g |
| publishDate | 2019 |
| publishDateSearch | 2019 |
| publishDateSort | 2019 |
| publisher | Shaker Verlag |
| record_format | marc |
| series2 | Schriftenreihe Mikrotechnik |
| spellingShingle | Thies, Jan-Wilhelm 1985- Particle enhanced point of care diagnostics utilizing quartz crystal microbalances Mikrowaage (DE-588)4169866-6 gnd Superparamagnetismus (DE-588)4608043-0 gnd Nanopartikel (DE-588)4333369-2 gnd Lab on a Chip (DE-588)7610677-9 gnd Schwingquarz (DE-588)4180559-8 gnd Empfindlichkeit (DE-588)4127339-4 gnd Geräteentwicklung (DE-588)4267986-2 gnd |
| subject_GND | (DE-588)4169866-6 (DE-588)4608043-0 (DE-588)4333369-2 (DE-588)7610677-9 (DE-588)4180559-8 (DE-588)4127339-4 (DE-588)4267986-2 (DE-588)4113937-9 |
| title | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances |
| title_auth | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances |
| title_exact_search | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances |
| title_full | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances Jan-Wilhelm Thies |
| title_fullStr | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances Jan-Wilhelm Thies |
| title_full_unstemmed | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances Jan-Wilhelm Thies |
| title_short | Particle enhanced point of care diagnostics utilizing quartz crystal microbalances |
| title_sort | particle enhanced point of care diagnostics utilizing quartz crystal microbalances |
| topic | Mikrowaage (DE-588)4169866-6 gnd Superparamagnetismus (DE-588)4608043-0 gnd Nanopartikel (DE-588)4333369-2 gnd Lab on a Chip (DE-588)7610677-9 gnd Schwingquarz (DE-588)4180559-8 gnd Empfindlichkeit (DE-588)4127339-4 gnd Geräteentwicklung (DE-588)4267986-2 gnd |
| topic_facet | Mikrowaage Superparamagnetismus Nanopartikel Lab on a Chip Schwingquarz Empfindlichkeit Geräteentwicklung Hochschulschrift |
| url | https://d-nb.info/1188836641/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031610390&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT thiesjanwilhelm particleenhancedpointofcarediagnosticsutilizingquartzcrystalmicrobalances |