Clinical Application of Radiolabelled Platelets
AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific...
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1990
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| Schriftenreihe: | Developments in Nuclear Medicine
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| 245 | 1 | 0 | |a Clinical Application of Radiolabelled Platelets |c edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici |
| 264 | 1 | |a Dordrecht |b Springer Netherlands |c 1990 | |
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| 520 | |a AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D. | ||
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Datensatz im Suchindex
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| genre_facet | Konferenzschrift 1987 Köln |
| id | DE-604.BV046144434 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:25Z |
| institution | BVB |
| isbn | 9789400905818 |
| language | English |
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| spelling | Clinical Application of Radiolabelled Platelets edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici Dordrecht Springer Netherlands 1990 1 Online-Ressource (301 p) txt rdacontent c rdamedia cr rdacarrier Developments in Nuclear Medicine 17 AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D. Nuclear Medicine Hematology Internal Medicine Cardiology Nuclear medicine Internal medicine Thrombozyt (DE-588)4059964-4 gnd rswk-swf Szintigraphie (DE-588)4058828-2 gnd rswk-swf Radionuklid (DE-588)4133541-7 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1987 Köln gnd-content Thrombozyt (DE-588)4059964-4 s Radionuklid (DE-588)4133541-7 s DE-604 Szintigraphie (DE-588)4058828-2 s Kessler, Ch edt Hardeman, M. R. edt Henningsen, H. edt Petrovici, J.-N. edt Erscheint auch als Druck-Ausgabe 9789401067492 Erscheint auch als Druck-Ausgabe 9780792307297 Erscheint auch als Druck-Ausgabe 9789400905825 https://doi.org/10.1007/978-94-009-0581-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Clinical Application of Radiolabelled Platelets Nuclear Medicine Hematology Internal Medicine Cardiology Nuclear medicine Internal medicine Thrombozyt (DE-588)4059964-4 gnd Szintigraphie (DE-588)4058828-2 gnd Radionuklid (DE-588)4133541-7 gnd |
| subject_GND | (DE-588)4059964-4 (DE-588)4058828-2 (DE-588)4133541-7 (DE-588)1071861417 |
| title | Clinical Application of Radiolabelled Platelets |
| title_auth | Clinical Application of Radiolabelled Platelets |
| title_exact_search | Clinical Application of Radiolabelled Platelets |
| title_full | Clinical Application of Radiolabelled Platelets edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici |
| title_fullStr | Clinical Application of Radiolabelled Platelets edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici |
| title_full_unstemmed | Clinical Application of Radiolabelled Platelets edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici |
| title_short | Clinical Application of Radiolabelled Platelets |
| title_sort | clinical application of radiolabelled platelets |
| topic | Nuclear Medicine Hematology Internal Medicine Cardiology Nuclear medicine Internal medicine Thrombozyt (DE-588)4059964-4 gnd Szintigraphie (DE-588)4058828-2 gnd Radionuklid (DE-588)4133541-7 gnd |
| topic_facet | Nuclear Medicine Hematology Internal Medicine Cardiology Nuclear medicine Internal medicine Thrombozyt Szintigraphie Radionuklid Konferenzschrift 1987 Köln |
| url | https://doi.org/10.1007/978-94-009-0581-8 |
| work_keys_str_mv | AT kesslerch clinicalapplicationofradiolabelledplatelets AT hardemanmr clinicalapplicationofradiolabelledplatelets AT henningsenh clinicalapplicationofradiolabelledplatelets AT petrovicijn clinicalapplicationofradiolabelledplatelets |