The SV40 replicon model for analysis of anticancer drugs
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
[San Diego, Calif.]
Academic Press ; Austin, TX R.G. Landes
1996
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| Schriftenreihe: | Molecular biology intelligence unit (Unnumbered)
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Inhaltsangabe:
- This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments