Immunotoxin Methods and Protocols
More potent and selective for killing cancer cells than chemotherapy, immunotoxins constitute a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized. In Immunotoxin Methods and Protocols, leading experts from laboratories around the...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
|
| Schriftenreihe: | Methods in Molecular Biology™
166 |
| Schlagworte: | |
| Online-Zugang: | DE-355 DE-91 URL des Erstveröffentlichers |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
MARC
| LEADER | 00000nam a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044952264 | ||
| 003 | DE-604 | ||
| 005 | 20180906 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180517s2001 xx o|||| 00||| eng d | ||
| 020 | |a 9781592591145 |9 978-1-59259-114-5 | ||
| 024 | 7 | |a 10.1385/1592591140 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-59259-114-5 | ||
| 035 | |a (OCoLC)730584175 | ||
| 035 | |a (DE-599)BVBBV044952264 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-91 | ||
| 050 | 0 | |a QR185.8.A58 | |
| 082 | 0 | |a 615/.373 |2 21 | |
| 082 | 0 | |a 616.079 |2 23 | |
| 084 | |a WC 4150 |0 (DE-625)148092: |2 rvk | ||
| 245 | 1 | 0 | |a Immunotoxin Methods and Protocols |c edited by Walter A. Hall |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2001 | |
| 300 | |a 1 Online-Ressource (XI, 297 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Biology™ |v 166 | |
| 520 | |a More potent and selective for killing cancer cells than chemotherapy, immunotoxins constitute a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized. In Immunotoxin Methods and Protocols, leading experts from laboratories around the world describe in step-by-step detail their cutting-edge methods for developing and applying these powerful proteins. The conjugates created by these researchers contain entire monoclonal antibodies, single chain antibody fragments, and cytokines as their carrier ligands. Their toxic portion can include such conventional chemotherapeutics as doxirubicin, such ribosome-inactivating proteins as the ricin A chain or saporin, or such bacterial toxins as diptheria toxin. Also described are a variety of applications that demonstrate the versatility of these agents, including the treatment of primary malignant brain tumors, the generation of selective brain lesions to localize critical functions, and the targeting of the AIDS virus. Each readily reproducible method is optimized for experimental success with hands-on instructions, invaluable notes on pitfalls to avoid, and informative explanations of why certain steps are necessary. Authoritative and highly practical, Immunotoxin Methods and Protocols provides today's cancer researchers, neuroscientists, and oncologists with state-of-the-art tools for exploring these powerful biological agents and their rapidly increasing applications | ||
| 650 | 4 | |a Biomedicine | |
| 650 | 4 | |a Immunology | |
| 650 | 4 | |a Medicine | |
| 650 | 4 | |a Immunology | |
| 650 | 0 | 7 | |a Pharmakologie |0 (DE-588)4045687-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Immunotoxin |0 (DE-588)4209677-7 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Immunotoxin |0 (DE-588)4209677-7 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Immunotoxin |0 (DE-588)4209677-7 |D s |
| 689 | 1 | 1 | |a Pharmakologie |0 (DE-588)4045687-0 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Hall, Walter A. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780896037755 |
| 856 | 4 | 0 | |u https://doi.org/10.1385/1592591140 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-030345018 | |
| 966 | e | |u https://doi.org/10.1385/1592591140 |l DE-355 |p ZDB-2-PRO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1385/1592591140 |l DE-91 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| DE-BY-TUM_katkey | 2643289 |
|---|---|
| DE-BY-UBR_katkey | 6025392 |
| _version_ | 1822726603203936257 |
| any_adam_object | |
| author2 | Hall, Walter A. |
| author2_role | edt |
| author2_variant | w a h wa wah |
| author_facet | Hall, Walter A. |
| building | Verbundindex |
| bvnumber | BV044952264 |
| callnumber-first | Q - Science |
| callnumber-label | QR185 |
| callnumber-raw | QR185.8.A58 |
| callnumber-search | QR185.8.A58 |
| callnumber-sort | QR 3185.8 A58 |
| callnumber-subject | QR - Microbiology |
| classification_rvk | WC 4150 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-59259-114-5 (OCoLC)730584175 (DE-599)BVBBV044952264 |
| dewey-full | 615/.373 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics 616 - Diseases |
| dewey-raw | 615/.373 616.079 |
| dewey-search | 615/.373 616.079 |
| dewey-sort | 3615 3373 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1385/1592591140 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03467nam a2200565zcb4500</leader><controlfield tag="001">BV044952264</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20180906 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2001 xx o|||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781592591145</subfield><subfield code="9">978-1-59259-114-5</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1385/1592591140</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-59259-114-5</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)730584175</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044952264</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QR185.8.A58</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615/.373</subfield><subfield code="2">21</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.079</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4150</subfield><subfield code="0">(DE-625)148092:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Immunotoxin Methods and Protocols</subfield><subfield code="c">edited by Walter A. Hall</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2001</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XI, 297 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology™</subfield><subfield code="v">166</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">More potent and selective for killing cancer cells than chemotherapy, immunotoxins constitute a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized. In Immunotoxin Methods and Protocols, leading experts from laboratories around the world describe in step-by-step detail their cutting-edge methods for developing and applying these powerful proteins. The conjugates created by these researchers contain entire monoclonal antibodies, single chain antibody fragments, and cytokines as their carrier ligands. Their toxic portion can include such conventional chemotherapeutics as doxirubicin, such ribosome-inactivating proteins as the ricin A chain or saporin, or such bacterial toxins as diptheria toxin. Also described are a variety of applications that demonstrate the versatility of these agents, including the treatment of primary malignant brain tumors, the generation of selective brain lesions to localize critical functions, and the targeting of the AIDS virus. Each readily reproducible method is optimized for experimental success with hands-on instructions, invaluable notes on pitfalls to avoid, and informative explanations of why certain steps are necessary. Authoritative and highly practical, Immunotoxin Methods and Protocols provides today's cancer researchers, neuroscientists, and oncologists with state-of-the-art tools for exploring these powerful biological agents and their rapidly increasing applications</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakologie</subfield><subfield code="0">(DE-588)4045687-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Immunotoxin</subfield><subfield code="0">(DE-588)4209677-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Immunotoxin</subfield><subfield code="0">(DE-588)4209677-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Immunotoxin</subfield><subfield code="0">(DE-588)4209677-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Pharmakologie</subfield><subfield code="0">(DE-588)4045687-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hall, Walter A.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780896037755</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1385/1592591140</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030345018</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1385/1592591140</subfield><subfield code="l">DE-355</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1385/1592591140</subfield><subfield code="l">DE-91</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV044952264 |
| illustrated | Not Illustrated |
| indexdate | 2024-12-24T06:25:55Z |
| institution | BVB |
| isbn | 9781592591145 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030345018 |
| oclc_num | 730584175 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (XI, 297 p) |
| psigel | ZDB-2-PRO |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Methods in Molecular Biology™ |
| spellingShingle | Immunotoxin Methods and Protocols Biomedicine Immunology Medicine Pharmakologie (DE-588)4045687-0 gnd Immunotoxin (DE-588)4209677-7 gnd |
| subject_GND | (DE-588)4045687-0 (DE-588)4209677-7 (DE-588)4143413-4 |
| title | Immunotoxin Methods and Protocols |
| title_auth | Immunotoxin Methods and Protocols |
| title_exact_search | Immunotoxin Methods and Protocols |
| title_full | Immunotoxin Methods and Protocols edited by Walter A. Hall |
| title_fullStr | Immunotoxin Methods and Protocols edited by Walter A. Hall |
| title_full_unstemmed | Immunotoxin Methods and Protocols edited by Walter A. Hall |
| title_short | Immunotoxin Methods and Protocols |
| title_sort | immunotoxin methods and protocols |
| topic | Biomedicine Immunology Medicine Pharmakologie (DE-588)4045687-0 gnd Immunotoxin (DE-588)4209677-7 gnd |
| topic_facet | Biomedicine Immunology Medicine Pharmakologie Immunotoxin Aufsatzsammlung |
| url | https://doi.org/10.1385/1592591140 |
| work_keys_str_mv | AT hallwaltera immunotoxinmethodsandprotocols |