Evaluation and management of vulvar disease

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Weitere Verfasser: Venkatesan, Aruna (HerausgeberIn)
Format: Buch
Sprache:English
Veröffentlicht: Philadelphia, Pennsylvania Elsevier [2017]
Schriftenreihe:Obstetrics and gynecology clinics of North America volume 44, number 3 (September 2017)
Online-Zugang:Inhaltsverzeichnis
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adam_text Titel: Evaluation and management of vulvar disease Autor: Venkatesan, Aruna Jahr: 2017 Evaluation and Management of Vulvar Disease Contents Foreword: Differentiating Between Normal, Benign, and Potentially Serious Vulvar Conditions William F. Rayburn xi Preface: Evaluation and Management of Vulvar Disease Aruna Venkatesan xiii A General Approach to the Evaluation and the Management of Vulvar Disorders 321 Gabriela A. Cobos and Miriam Keltz Pomeranz The evaluation of the vulva should always begin with a detailed clinical his- tory. The clinician should be very familiar with vulvar anatomy and the changes it undergoes depending on the patient s age and hormonal sta- tus. A systematic approach should be developed when examining the vulva so as to not leave out any parts. Finally, there is a wide array of ancil- lary tests and diagnostic procedures that can be pursued to arrive at the correct diagnosis and begin proper management. High-Yield Vulvar Histopathology for the Clinician 329 Jason C. Reutter Certain adjustable factors may influence how helpful a pathology report is to the clinician. Different biopsy techniques may be preferable based on the type of lesion being biopsied and the background epithelial surface. Key observations from the history and physical examination, possibly with a clinical photograph, are helpful to the pathologist. When reading the pathology report, the clinician should realize the difficulties arising from definitively classifying some diseases and how treatment can affect the tissue. Finally, miscommunication with the pathologist must be avoided by understanding the current nomenclature of vulvar disease. Vulvar Neoplasms, Benign and Malignant 339 Jill I. Allbritton Cutaneous vulvar neoplasms are commonly encountered at gynecology visits, with 2% of women having a benign vulvar melanocytic nevus and 10% to 12% of nevi being vulvar. High-grade squamous intraepithelial le- sions (vulvar intraepithelial neoplasia 2 or 3) occur in 5 per 100,000 women, with an Increasing incidence in the past 30 years. The recognition of these lesions and differentiation between benign, premalignant, and malignant stages are crucial for adequate diagnosis, clinical monitoring, and treat- ment. The presentation, diagnosis, and management of benign and malig- nant vulvar proliferations are discussed with focus on the practical aspects of clinical care. Contents Red Rashes of the Vulva Lynne H. Morrison and Catherine M. Leclair Red patches and plaques of the vulva may be manifestations of neo- plasms, infections, or inflammatory skin diseases. These diseases can mimic one another clinically; features that generally allow the diseases to be identified on most cutaneous surfaces can be altered in the moist, occluded vulvar environment, making clinical diagnosis difficult. A detailed history and thorough physical examination can point to the likely diagnosis, but biopsy and culture may be needed for diagnosis especially in refractory disease. It is not uncommon for several of these processes to be present concomitantly or complicating other vulvar diseases. Atopic and Contact Dermatitis of the Vulva Rita Pichardo-Geisinger Pruritus, or itch, is a common vulvar complaint that is often treated empir- ically as a yeast infection; however, yeast infections are just one of the many conditions that can cause vulvar itch. Ignoring other conditions can prolong pruritus unnecessarily. Atopic dermatitis, irritant contact dermatitis, and allergic contact dermatitis are extremely common noninfectious causes of vulvar itch that are often underdiagnosed by nondermatologists. Identifying these conditions and treating them appro- priately can significantly improve a patient s quality of life and appropri- ately decrease health care expenditures by preventing unnecessary additional referrals or follow-up visits and decreasing pharmaceutical costs. Vulvar Pruritus and Lichen Simplex Chronicus Rebecca Chibnall Vulvar pruritus and lichen simplex chronicus are common reasons for presentation to women s health practitioners, including gynecologists and dermatologists. Both conditions are multifactorial and are often confounded by other inflammatory, neoplastic, infectious, environmental, neuropathic, hormonal, and behavioral variables. Careful history taking and thorough physical examinations, including wet mount and potentially skin biopsy, are necessary for appropriate diagnosis. Treatment should focus on decreasing inflammation, reducing irritants, and providing symp- tomatic relief to achieve remission. Comprehensive treatment covering environmental, biological, and behavioral therapy can result in long-term cure for patients with these conditions. Genital Lichen Sderosus and its Mimics Anuja Vyas A variety of disorders may be confused with vulvar or genital lichen scle- rosus, as they can share several common features. This article dis- cusses the diagnosis, workup, and management of vulvar lichen sclerosus, with specific attention on distinguishing it from other derma- tologie mimics. Contents vii Erosive Lichen Planus 407 Melissa Mauskar Liehen planus is an inflammatory mucocutaneous condition with a myriad of clinical manifestations. There are 3 forms of lichen planus that affect the vulva: papulosquamous, hypertrophic, and erosive. Erosive lichen planus can progress to vulvar scaring, vaginal stenosis, and squamous cell carci- noma: these long-term sequelae cause sexual distress, depression, and decreased quality of life for patients. Diagnosis is often delayed because of patient embarrassment or clinician misdiagnosis. Early recognition and treatment is essential to decreasing the morbidity of this condition. Multimodal treatment, along with a multidisciplinary approach, will improve outcomes and further clinical advances in studying this condition. Fissures, Herpes Simplex Virus, and Drug Reactions: Important Erosive Vulvar Disorders 421 Tanja G. Bohl Vulvar fissures, excoriations, and erosions are common problems resulting from a variety of causes, many involving other mucosal and cutaneous sites. The authors present historical and examination features and useful investigations that can help establish a diagnosis so that definitive therapy can be instituted. Vulvar involvement also can be part of life-threatening conditions that require hospital admission and a multidisciplinary approach for optimal patient care. The clinical morphology of these exam- ination findings and response to therapy can be modified by various host factors, particularly immune status, and atypical presentations and re- sponses to therapy should always prompt patient réévaluation. A Clinical Approach to Vulvar Ulcers 445 Kristen M.A. Stewart This article discusses the differential diagnosis of vulvar ulcers and describes a general clinical approach to this common but nonspecific ex- amination finding. The differential diagnosis includes sexually and nonsex- ual^ transmitted infections, dermatitides, trauma, neoplasms, hormonally induced ulcers, and drug reactions. Patient history and physical examina- tion provide important clues to the cause of a vulvar ulcer. However, lab- oratory testing is usually required for accurate diagnosis because the clinical presentation is often nonspecific and may be atypical due to sec- ondary conditions. Challenging Ulcerative Vulvar Conditions: Hidradenitis Suppurativa, Crohn Disease, and Aphthous Ulcers 453 Kristen M.A. Stewart This article discusses the clinical evaluation and approach to patients with 3 complex ulcerative vulvar conditions: hidradenitis suppurativa, metasta- tic Crohn disease of the vulva, and aphthous ulcers. These conditions are particularly challenging to medical providers because, although each is known to present with nonspecific examination findings that vary in morphology, the predominance of the diagnosis is based on clinical exam- ination and exclusion of a wide variety of other conditions. Care of patients Contents with these conditions is further complicated by the lack of therapeutic data and the significant impact these conditions have on quality of life. Vulvovaginal Graft-Versus-Host Disease Rachel I. Komik and Alison S. Rustagi Vulvovaginal chronic graft-versus-host disease (cGVHD) is an underrecog- nized complication of stem cell transplantation. Early recognition may prevent severe sequelae. Genital involvement is associated with oral, ocular, and skin manifestations. Treatment includes topical immunosup- pression, dilator use, and adjuvant topical estrogen. Clinical and histologic features may mimic other inflammatory vulvar conditions. In the right clinical context, these findings are diagnostic of cGVHD. Female recipients of allo-hematopoietic stem cell transplantation (HCT) are at higher risk of condylomas, cervical dysplasia, and neoplasia. The National Institutes of Health publishes guidelines for the diagnosis, grading, management, and supportive care for HCT patients by organ system. Vulvodynia: Diagnosis and Management Amy L. Stenson Vulvodynia is a common condition that negatively affects sexual health and quality of life for many women. A new classification system that di- vides vulvodynia into subtypes based on pain characteristics has been adopted. Diagnosis relies on ruling out possible contributing pathologic conditions. A multidisciplinary approach to treatment is likely to achieve the best outcome for all types. Medical therapy with systemic neuromodu- lators is suggested for generalized vulvodynia. For patients with vestibulo- dynia, topical therapy may be beneficial. Vestibulectomy has a high success rate and may be a good option if the patient is not responding to treatment. Pelvic Floor Physical Therapy for Vulvodynia: A Clinician s Guide Stephanie A. Prendergast Vulvar pain affects up to 20% of women at some point in their lives, and most women with vulvar pain have associated pelvic floor impairments. Pelvic floor dysfunction is associated with significant functional limitations in women by causing painful intercourse and urinary, bowel, and sexual dysfunction. A quick screening of the pelvic floor muscles can be per- formed in the gynecology office and should be used when patients report symptoms of pelvic pain. It is now known the vulvar pain syndromes are heterogeneous in origin; therefore, successful treatment plans are multi- modal and include physical therapy.
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spellingShingle Evaluation and management of vulvar disease
Obstetrics and gynecology clinics of North America
title Evaluation and management of vulvar disease
title_auth Evaluation and management of vulvar disease
title_exact_search Evaluation and management of vulvar disease
title_full Evaluation and management of vulvar disease editor Aruna Venkatesan
title_fullStr Evaluation and management of vulvar disease editor Aruna Venkatesan
title_full_unstemmed Evaluation and management of vulvar disease editor Aruna Venkatesan
title_short Evaluation and management of vulvar disease
title_sort evaluation and management of vulvar disease
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