Enzyme regulation in metabolic pathways
Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism. It provides a means of correlating data obtained in experimental studies to multiple possible mechanisms through which some enzyme may catalyze the...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley Blackwell
2017
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| Online-Zugang: | DE-861 DE-473 URL des Erstveröffentlichers Inhaltsverzeichnis |
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| 245 | 1 | 0 | |a Enzyme regulation in metabolic pathways |c Lloyd Wolfinbarger |
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| 520 | |a Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism. It provides a means of correlating data obtained in experimental studies to multiple possible mechanisms through which some enzyme may catalyze the conversion of a substrate to a product. Although not the most appropriate means of determining some potential kinetic mechanism, quasi-equilibrium assumptions are used throughout the book, keeping the rate equation derivations simple. Actual metabolic pathways with known (presumed) positive and negative regulation events are linked to these potential kinetic mechanisms using both rate equation derivations and data plots illustrating how the rate equation derivations can be used to explain the data plots. This book will be a valuable reference for students in biological sciences and biochemistry majors required to take a core course in enzymology | ||
| 650 | 7 | |a Enzymes / Regulation |2 fast | |
| 650 | 7 | |a SCIENCE / Life Sciences / Cell Biology |2 bisacsh | |
| 650 | 4 | |a Enzymes |x Regulation | |
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Contents
Preface vii
Author s Review ix
Parti
Characteristics of Enzymes 3
Self-Assembly of Polymers 17
Beginnings of Equations 27
Metabolite Distribution Systems 37
Modification of Enzymatic Activity 51
Modification of Metabolite Flow Through Metabolic Pathways 67
Which is the Real Substrate? 75
Non-Quasi-Equilibrium Assumptions 79
Underlying Attributes of Assessing Enzymatic Activities 85
Part II
Breakdown of the Michaelis-Menten Equation (or Complex Enzyme
Mechanisms) 97
Rate Equation Derivation by the King-Altman Method: Two Substrates
and Two Products 117
vi Contents
12 Modification of Enzyme Mechanisms: The Next Generation 141
13 What Are These Rate Constants We Have Been Dealing With? 151
|
| any_adam_object | 1 |
| author | Wolfinbarger, Lloyd |
| author_GND | (DE-588)1131819276 |
| author_facet | Wolfinbarger, Lloyd |
| author_role | aut |
| author_sort | Wolfinbarger, Lloyd |
| author_variant | l w lw |
| building | Verbundindex |
| bvnumber | BV044442473 |
| collection | ZDB-35-WIC |
| ctrlnum | (ZDB-35-WIC)971547363 (OCoLC)971547363 (DE-599)BVBBV044442473 |
| dewey-full | 572/.74 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.74 |
| dewey-search | 572/.74 |
| dewey-sort | 3572 274 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
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| id | DE-604.BV044442473 |
| illustrated | Illustrated |
| indexdate | 2024-12-24T06:08:13Z |
| institution | BVB |
| isbn | 9781119155423 1119155428 |
| language | English |
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| oclc_num | 971547363 |
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| physical | 1 online resource illustrations |
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| publishDate | 2017 |
| publishDateSearch | 2017 |
| publishDateSort | 2017 |
| publisher | Wiley Blackwell |
| record_format | marc |
| spellingShingle | Wolfinbarger, Lloyd Enzyme regulation in metabolic pathways Enzymes / Regulation fast SCIENCE / Life Sciences / Cell Biology bisacsh Enzymes Regulation |
| title | Enzyme regulation in metabolic pathways |
| title_auth | Enzyme regulation in metabolic pathways |
| title_exact_search | Enzyme regulation in metabolic pathways |
| title_full | Enzyme regulation in metabolic pathways Lloyd Wolfinbarger |
| title_fullStr | Enzyme regulation in metabolic pathways Lloyd Wolfinbarger |
| title_full_unstemmed | Enzyme regulation in metabolic pathways Lloyd Wolfinbarger |
| title_short | Enzyme regulation in metabolic pathways |
| title_sort | enzyme regulation in metabolic pathways |
| topic | Enzymes / Regulation fast SCIENCE / Life Sciences / Cell Biology bisacsh Enzymes Regulation |
| topic_facet | Enzymes / Regulation SCIENCE / Life Sciences / Cell Biology Enzymes Regulation |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9781119155423 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029843605&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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