The vitamins fundamental aspects in nutrition and health
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| Format: | Buch |
| Sprache: | English |
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Amsterdam
Academic Press
[2017]
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| Ausgabe: | Fifth edition |
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Datensatz im Suchindex
| _version_ | 1804177467532902400 |
|---|---|
| adam_text | Contents
Preface to the Fifth Edition
How to Use This Book
Part I
Perspectives on the Vitamins in
Nutrition
1. What Is a Vitamin?
1. Thinking About Vitamins
2. Vitamin: A Revolutionary Concept
3. An Operating Definition of a Vitamin
4. The Recognized Vitamins
5. Study Questions and Exercises
2. Discovery of the Vitamins
1. The Emergence of Nutrition as a Science
2. The Process of Discovery in Nutritional
Science
3. The Empirical Phase of Vitamin Discovery
4. The Experimental Phase of Vitamin
Discovery
5. The Vitamine Theory
6. Elucidation of the Vitamins
7. Vitamin Terminology
8. Other Factors Sometimes Called Vitamins
9. Modern History of the Vitamins
10. Study Questions and Exercises
Recommended Reading
3. General Properties of Vitamins
1. Vitamin Nomenclature
2. Chemical and Physical Properties of the
Vitamins
3. Physiological Utilization of the Vitamins
4. Metabolism of the Vitamins
5. Metabolic Functions of the Vitamins
6. Vitamin Bioavailability
7. Vitamin Analysis
8. Study Questions and Exercises 58
Recommended Reading 58
4. Vitamin Deficiency
1. The Concept of Vitamin Deficiency 60
2. Clinical Manifestations of Vitamin
Deficiencies 61
3. Causes of Vitamin Deficiencies 65
4. Study Questions and Exercises 78
Recommended Reading 78
5. Vitamin Needs and Safety
1. Dietary Standards for Vitamins 80
2. Vitamin Allowances for Humans 87
3. Vitamin Allowances for Animals 89
4. Uses of Vitamins Above Required
Levels 89
5. Hypervitaminoses 96
6. Safe Intakes of Vitamins 102
7. Study Questions and Exercises 105
Recommended Reading 105
Part II
Considering the Individual Vitamins
6. Vitamin A
1. Significance of Vitamin A 110
2. Properties of Vitamin A 111
3. Sources of Vitamin A 112
4. Absorption of Vitamin A 115
5. Transport of Vitamin A 118
6. Metabolism of Vitamin A 125
7. Metabolic Functions of Vitamin A 129
8. Biomarkers of Vitamin A Status 137
9. Vitamin A Deficiency 139
10. Vitamin A in Health and Disease 147
11. Vitamin A Toxicity 153
12. CaseStudies 156
13. Study Questions and Exercises 158
Recommended Reading 159
vii
xi
xiii
3
3
4
5
5
8
8
8
12
14
18
28
28
29
30
30
34
36
43
50
51
52
52
viii Contents
7. Vitamin D
1. Significance of Vitamin D 162
2. Properties of Vitamin D 163
3. Sources of Vitamin D 164
4. Enteric Absorption of Vitamin D 170
5. Transport of Vitamin D 171
6. Metabolism of Vitamin D 173
7. Metabolic Functions of Vitamin D 176
8. Biomarkers of Vitamin D Status 190
9. Vitamin D Deficiency 192
10. Vitamin D in Health and Disease 198
11. Vitamin D Toxicity 202
12. CaseStudies 204
13. Study Questions and Exercises 205
Recommended Reading 205
8. Vitamin E
1. Significance of Vitamin E 208
2. Properties of Vitamin E 208
3. Sources of Vitamin E 210
4. Absorption of Vitamin E 212
5. Transport of Vitamin E 214
6. Metabolism of Vitamin E 219
7. Metabolic Functions of Vitamin E 221
8. Biomarkers of Vitamin E Status 227
9. Vitamin E Deficiency 229
10. Vitamin E in Health and Disease 231
11. Vitamin E Toxicity 239
12. Case Studies 240
13. Study Questions and Exercises 241
Recommended Reading 241
9. Vitamin K
1. The Significance of Vitamin K 244
2. Properties of Vitamin K 244
3. Sources of Vitamin K 245
4. Absorption of Vitamin K 249
5. Transport of Vitamin K 249
6. Metabolism of Vitamin K 250
7. Metabolic Functions of Vitamin K 253
8. Biomarkers of Vitamin K Status 258
9. Vitamin K Deficiency 259
10. Vitamin K Health and Disease 262
11. Vitamin K Toxicity 262
12. CaseStudies 263
13. Study Questions and Exercises 264
Recommended Reading 265
10. Vitamin C
1. The Significance of Vitamin C 268
2. Properties of Vitamin C 268
3. Sources of Vitamin C 269
4. Absorption of Vitamin C 272
5. Transport of Vitamin C 272
6. Metabolism of Vitamin C 274
7. Metabolic Functions of Vitamin C 275
8. Biomarkers of Vitamin C Status 283
9. Vitamin C Deficiency 284
10. Vitamin C in Health and Disease 286
11. Vitamin C Toxicity 292
12. Case Studies 293
13. Study Questions and Exercises 295
Recommended Reading 295
11. Thiamin
1. The Significance of Thiamin 298
2. Properties of Thiamin 298
3. Sources of Thiamin 299
4. Absorption of Thiamin 301
5. Transport of Thiamin 302
6. Metabolism of Thiamin 303
7. Metabolic Functions of Thiamin 304
8. Biomarkers of Thiamin Status 308
9. Thiamin Deficiency 309
10. Role of Thiamin in Health and Disease 312
11. Thiamin Toxicity 313
12. Case Studies 313
13. Study Questions and Exercises 314
Recommended Reading 314
12. Riboflavin
1. The Significance of Riboflavin 316
2. Properties of Riboflavin 316
3. Sources of Riboflavin 317
4. Absorption of Riboflavin 318
5. Transport of Riboflavin 319
6. Metabolism of Riboflavin 320
7. Metabolic Functions of Riboflavin 322
8. Biomarkers of Riboflavin Status 323
9. Riboflavin Deficiency 323
10. Riboflavin in Health and Disease 327
11. Riboflavin Toxicity 328
12. Case Study 328
13. Study Questions and Exercises 329
Recommended Reading 329
13. Niacin
1. The Significance of Niacin 332
2. Properties of Niacin 332
3. Sources of Niacin 333
4. Absorption of Niacin 334
5. Transport of Niacin 335
6. Metabolism of Niacin 336
7. Metabolic Functions of Niacin 340
Contents ix
8. Biomarkers of Niacin Status 342
9. Niacin Deficiency 343
10. Niacin in Health and Disease 344
11. Niacin Toxicity 348
12. Case Study 348
13. Study Questions and Exercises 349
Recommended Reading 349
10. Pantothenic Acid in Health and Disease 396
11. Pantothenic Acid Toxicity 397
12. Case Study 397
13. Study Questions and Exercises 398
Recommended Reading 398
17. Folate
14. Vitamin B6
1. The Significance of Vitamin B6 352
2. Properties of Vitamin B6 352
3. Sources of Vitamin B6 352
4. Absorption of Vitamin B6 353
5. Transport of Vitamin B6 355
6. Metabolism of Vitamin B6 356
7. Metabolic Functions of Vitamin B6 358
8. Biomarkers of Vitamin B6 Status 365
9. Vitamin B6 Deficiency 366
10. Vitamin B6 in Health and Disease 367
11. Vitamin B6 Toxicity 369
12. Case Studies 369
13. Study Questions and Exercises 370
Recommended Reading 370
15. Biotin
1. The Significance of Biotin 372
2. Properties of Biotin 372
3. Sources of Biotin 372
4. Absorption of Biotin 374
5. Transport of Biotin 374
6. Metabolism of Biotin 376
7. Metabolic Functions of Biotin 376
8. Biomarkers of Biotin Status 380
9. Biotin Deficiency 380
10. Biotin in Health and Disease 382
11. Biotin Toxicity 383
12. Case Study 383
13. Study Questions and Exercises 384
Recommended Reading 384
16. Pantothenic Add
1. The Significance of Pantothenic Acid 388
2. Properties of Pantothenic Acid 388
3. Sources of Pantothenic Acid 388
4. Absorption of Pantothenic Acid 389
5. Transport of Pantothenic Acid 390
6. Metabolism of Pantothenic Acid 391
7. Metabolic Functions of Pantothenic
Acid 393
8. Biomarkers of Pantothenic Acid
Status 395
9. Pantothenic Acid Deficiency 395
1. The Significance of Folate 400
2. Properties of Folate 400
3. Sources of Folate 402
4. Absorption of Folate 404
5. Transport of Folate 406
6. Metabolism of Folate 408
7. Metabolic Functions of Folate 413
8. Biomarkers of Folate Status 419
9. Folate Deficiency 420
10. Folate in Health and Disease 425
11. Folate Toxicity 427
12. Case Study 427
13. Study Questions and Exercises 428
Recommended Reading 428
18. Vitamin B12
1. Significance of Vitamin B12 432
2. Properties of Vitamin B12 432
3. Sources of Vitamin B12 433
4. Absorption of Vitamin B12 435
5. Transport of Vitamin B12 436
6. Metabolism of Vitamin B12 439
7. Metabolic Functions of Vitamin B12 440
8. Biomarkers of Vitamin B12 Status 443
9. Vitamin B12 Deficiency 444
10. Vitamin B12 in Health and Disease 450
11. Vitamin B12 Toxicity 450
12. Case Study 450
13. Study Questions and Exercises 451
Recommended Reading 452
19. Vitamin-Like Factors
1. Is the List of Vitamins Complete? 454
2. Choline 455
3. Carnitine 462
4. Myo-lnositol 469
5. Ubiquinones 474
6. LipoicAcid 477
7. Nonprovitamin A Carotenoids 480
8. Flavonoids 487
9. Orotic Acid 494
10. Unidentified Factors 495
11. Case Study 496
12. Study Questions and Exercises 496
Recommended Reading 497
x Contents
Partlll
Using Current Knowledge of the
Vitamins
20. Sources of the Vitamins
1. Vitamins in Foods and Feedstuffs 501
2. Vitamin Bioavailability 508
3. Vitamin Losses in Foods 509
4. Vitamin Fortification 511
5. Biofortification 513
6. Vitamin Labeling of Foods 516
7. Vitamins in Human Diets 517
8. Vitamin Supplementation 521
9. Vitamins in Livestock Feeding 523
10. Case Study 528
11. Study Questions and Exercises 530
Recommended Reading 530
Assessing Vitamin Status
1. Nutritional Assessment 531
2.’ Biomarkers of Vitamin Status 533
3. Vitamin Status of Human Populations 534
4. Global Undernutrition 541
5. Study Questions and Exercises 543
Recommended Reading 543
Appendix A: Current and Obsolete Designations
of Vitamins (Bolded) and Other
Vitamin-Like Factors 545
Appendix B: Original Reports for Case Studies 549
Appendix C: A Core of Current Vitamin Literature 551
Appendix D: Vitamin Contents of Foods (units per
100g Edible Portion) 559
Appendix E: Vitamin Contents of Feedstuffs
(units per kg) 589
index 593
Fundamental Aspects in Nutrition and Health
Gerald F. Combs, Jr., Professor Emeritus, Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
James P. McClung Westborough, Massachusetts, USA
The Vitamins: Fundamental Aspects in Nutrition and Health, Fifth Edition, provides the latest coverage of
the biochemistry and physiology of vitamins and vitamin-like substances. The text includes insights into the
biochemical function of vitamins, not only for general nutritional health, but also in the prevention and/or
treatment of specific health issues, such as immunity, inflammation, obesity, and anemia.
Readers will gain an understanding of the contributions of the gut microbiome to vitamin nutrition, and of
the roles of vitamins in gene expression and epigenetics, providing important Information relevant to the
potential for personalized medicine and dietary programs based on Individual genetic profiles.
The cohesive, carefully organized, and easy-to-read presentation of each vitamin includes key words, case
studies, and detail regarding dietary requirements and metabolic function. The readability of this complex
content Is highly regarded by students, instructors, researchers, and professionals alike.
New to this edition
• Updates of each chapter reflect the most recent Information regarding vitamin function
• Roles of the gut microbiome In vitamin metabolism and homeostasis
• Biomarkers of vitamin status
• Expanded detail regarding vitamin biofortification
• Additional tables and figures; others redrawn and updated
• Footnotes used as explanatory notes and for citing primary sources
ACADEMIC PRESS
An imprint of Elsevier
elsevier.com
|
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| spelling | Combs, Gerald F. Jr. Verfasser (DE-588)1127773054 aut The vitamins fundamental aspects in nutrition and health Gerald F. Combs, Jr., PH. D., James P. McClung, Ph. D. Fifth edition Amsterdam Academic Press [2017] xv, 612 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Literaturangaben Vitamins Nutritional Physiological Phenomena Nutrition Nutrição larpcal Vitaminas (metabolismo) larpcal Vitaminen gtt Vitamines Vitamin (DE-588)4063635-5 gnd rswk-swf Vitamin (DE-588)4063635-5 s 1\p DE-604 McClung, James P. Verfasser aut Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029683048&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029683048&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Combs, Gerald F. Jr McClung, James P. The vitamins fundamental aspects in nutrition and health Vitamins Nutritional Physiological Phenomena Nutrition Nutrição larpcal Vitaminas (metabolismo) larpcal Vitaminen gtt Vitamines Vitamin (DE-588)4063635-5 gnd |
| subject_GND | (DE-588)4063635-5 |
| title | The vitamins fundamental aspects in nutrition and health |
| title_auth | The vitamins fundamental aspects in nutrition and health |
| title_exact_search | The vitamins fundamental aspects in nutrition and health |
| title_full | The vitamins fundamental aspects in nutrition and health Gerald F. Combs, Jr., PH. D., James P. McClung, Ph. D. |
| title_fullStr | The vitamins fundamental aspects in nutrition and health Gerald F. Combs, Jr., PH. D., James P. McClung, Ph. D. |
| title_full_unstemmed | The vitamins fundamental aspects in nutrition and health Gerald F. Combs, Jr., PH. D., James P. McClung, Ph. D. |
| title_short | The vitamins |
| title_sort | the vitamins fundamental aspects in nutrition and health |
| title_sub | fundamental aspects in nutrition and health |
| topic | Vitamins Nutritional Physiological Phenomena Nutrition Nutrição larpcal Vitaminas (metabolismo) larpcal Vitaminen gtt Vitamines Vitamin (DE-588)4063635-5 gnd |
| topic_facet | Vitamins Nutritional Physiological Phenomena Nutrition Nutrição Vitaminas (metabolismo) Vitaminen Vitamines Vitamin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029683048&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029683048&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT combsgeraldf thevitaminsfundamentalaspectsinnutritionandhealth AT mcclungjamesp thevitaminsfundamentalaspectsinnutritionandhealth |