Rheumatic diseases immunological mechanisms and prospects for new therapies

This authoritative review volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the developmen...

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Bibliographische Detailangaben
Weitere Verfasser: Gaston, J. S. Hill 1952- (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Cambridge Cambridge University Press 1999
Schlagworte:
Online-Zugang:DE-12
DE-92
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Inhaltsangabe:
  • Ch. 1. Implications of advances in immunology for understanding the pathogenesis and treatment of rheumatic diseases
  • Ch. 2. The role of T cells in autoimmune disease
  • Ch. 3. The role of MHC antigens in autoimmunity
  • Ch. 4. B cells: formation and structure of autoantibodies
  • Ch. 5. The role of CD40 in immune responses
  • Ch. 6. Manipulation of the T cell immune system via CD28 and CTLA-4
  • Ch. 7. Lymphocyte antigen receptor signal transduction
  • Ch. 8. The role of adhesion mechanisms in inflammation
  • Ch. 9. The regulation of apoptosis in the rheumatic disorders
  • Ch. 10. The role of monokines in arthritis
  • Ch. 11. T lymphocyte subsets in relation to autoimmune disease
  • Ch. 12. Complement receptors