Autophagy, Part A lower eukaryotes and non-mammalian systems
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| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego, Calif.
Academic
c2008
|
| Schriftenreihe: | Methods in enzymology
v. 451 |
| Schlagworte: | |
| Online-Zugang: | UER01 FAW01 URL des Erstveröffentlichers |
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| 245 | 1 | 0 | |a Autophagy, Part A |b lower eukaryotes and non-mammalian systems |c edited by Daniel J. Klionsky |
| 264 | 1 | |a San Diego, Calif. |b Academic |c c2008 | |
| 300 | |a liv, 750 p., [16] p. of plates | ||
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| 490 | 0 | |a Methods in enzymology |v v. 451 | |
| 500 | |a Includes bibliographical references and indexes | ||
| 500 | |a This is the companion volume to Daniel Klionsky's Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, "Autophagy: from phenomenology to molecular understanding in less than a decade." He is currently editing guidelines for the field, with 230 contributing authors, that will publish in Autophagy. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. | ||
| 500 | |a (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. *Establishes the functional roles of specific cellular proteins in selective and nonselective autophagy in mammalian cells which aids researchers in determining why autophagy is shut down in neoplastia (growth of abnormal tissue mass) and turned on during bacterial invasion. *Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture, which helps researchers design clinical approaches that can turn on autophagy and halt tumor growth. *Covers higher eukaryotes including lifespan in C. | ||
| 500 | |a elegans to marine organisims and bridging into the clinical aspects, including autophagy in chronic myelogenous leukemia (CML is one of four types of leukaemia), lung cancer, prostate cancer, and cardiac cells | ||
| 650 | 7 | |a SCIENCE / Life Sciences / Anatomy & Physiology |2 bisacsh | |
| 650 | 7 | |a Autophagic vacuoles |2 fast | |
| 650 | 7 | |a Cell death |2 fast | |
| 650 | 7 | |a Eukaryotic cells |2 fast | |
| 650 | 4 | |a Cell Death | |
| 650 | 4 | |a Autophagy | |
| 650 | 4 | |a Eukaryotic cells | |
| 650 | 4 | |a Autophagic vacuoles | |
| 650 | 4 | |a Autophagy / Laboratory Manuals | |
| 650 | 4 | |a Cell Death / Laboratory Manuals | |
| 650 | 4 | |a Cell death | |
| 650 | 4 | |a Eukaryotic Cells / Laboratory Manuals | |
| 650 | 4 | |a Cell death | |
| 650 | 4 | |a Autophagic vacuoles | |
| 650 | 4 | |a Eukaryotic cells | |
| 700 | 1 | |a Klionsky, Daniel J. |e Sonstige |4 oth | |
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| id | DE-604.BV043877732 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:37:28Z |
| institution | BVB |
| isbn | 9780080923260 0080923267 9780123745484 0123745489 |
| language | English |
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| series2 | Methods in enzymology |
| spelling | Autophagy, Part A lower eukaryotes and non-mammalian systems edited by Daniel J. Klionsky San Diego, Calif. Academic c2008 liv, 750 p., [16] p. of plates txt rdacontent c rdamedia cr rdacarrier Methods in enzymology v. 451 Includes bibliographical references and indexes This is the companion volume to Daniel Klionsky's Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, "Autophagy: from phenomenology to molecular understanding in less than a decade." He is currently editing guidelines for the field, with 230 contributing authors, that will publish in Autophagy. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. *Establishes the functional roles of specific cellular proteins in selective and nonselective autophagy in mammalian cells which aids researchers in determining why autophagy is shut down in neoplastia (growth of abnormal tissue mass) and turned on during bacterial invasion. *Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture, which helps researchers design clinical approaches that can turn on autophagy and halt tumor growth. *Covers higher eukaryotes including lifespan in C. elegans to marine organisims and bridging into the clinical aspects, including autophagy in chronic myelogenous leukemia (CML is one of four types of leukaemia), lung cancer, prostate cancer, and cardiac cells SCIENCE / Life Sciences / Anatomy & Physiology bisacsh Autophagic vacuoles fast Cell death fast Eukaryotic cells fast Cell Death Autophagy Eukaryotic cells Autophagic vacuoles Autophagy / Laboratory Manuals Cell Death / Laboratory Manuals Cell death Eukaryotic Cells / Laboratory Manuals Klionsky, Daniel J. Sonstige oth http://www.sciencedirect.com/science/book/9780123745484 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Autophagy, Part A lower eukaryotes and non-mammalian systems SCIENCE / Life Sciences / Anatomy & Physiology bisacsh Autophagic vacuoles fast Cell death fast Eukaryotic cells fast Cell Death Autophagy Eukaryotic cells Autophagic vacuoles Autophagy / Laboratory Manuals Cell Death / Laboratory Manuals Cell death Eukaryotic Cells / Laboratory Manuals |
| title | Autophagy, Part A lower eukaryotes and non-mammalian systems |
| title_auth | Autophagy, Part A lower eukaryotes and non-mammalian systems |
| title_exact_search | Autophagy, Part A lower eukaryotes and non-mammalian systems |
| title_full | Autophagy, Part A lower eukaryotes and non-mammalian systems edited by Daniel J. Klionsky |
| title_fullStr | Autophagy, Part A lower eukaryotes and non-mammalian systems edited by Daniel J. Klionsky |
| title_full_unstemmed | Autophagy, Part A lower eukaryotes and non-mammalian systems edited by Daniel J. Klionsky |
| title_short | Autophagy, Part A |
| title_sort | autophagy part a lower eukaryotes and non mammalian systems |
| title_sub | lower eukaryotes and non-mammalian systems |
| topic | SCIENCE / Life Sciences / Anatomy & Physiology bisacsh Autophagic vacuoles fast Cell death fast Eukaryotic cells fast Cell Death Autophagy Eukaryotic cells Autophagic vacuoles Autophagy / Laboratory Manuals Cell Death / Laboratory Manuals Cell death Eukaryotic Cells / Laboratory Manuals |
| topic_facet | SCIENCE / Life Sciences / Anatomy & Physiology Autophagic vacuoles Cell death Eukaryotic cells Cell Death Autophagy Autophagy / Laboratory Manuals Cell Death / Laboratory Manuals Eukaryotic Cells / Laboratory Manuals |
| url | http://www.sciencedirect.com/science/book/9780123745484 |
| work_keys_str_mv | AT klionskydanielj autophagypartalowereukaryotesandnonmammaliansystems |