Human drug metabolism an introduction
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| Format: | Elektronisch E-Book |
| Sprache: | English |
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Oxford
Wiley-Blackwell
©2010
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| Ausgabe: | 2nd ed |
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| 245 | 1 | 0 | |a Human drug metabolism |b an introduction |c Michael D. Coleman |
| 250 | |a 2nd ed | ||
| 264 | 1 | |a Oxford |b Wiley-Blackwell |c ©2010 | |
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| 500 | |a Includes bibliographical references and index | ||
| 500 | |a (Publisher-supplied data) Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of changes in drug metabolism and its impact on patient welfare. After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolizing systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs | ||
| 650 | 4 | |a Pharmaceutical Preparations / metabolism | |
| 650 | 4 | |a Xenobiotics / toxicity | |
| 650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
| 650 | 7 | |a Drugs / Metabolism |2 fast | |
| 650 | 7 | |a Drugs / Physiological effect |2 fast | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Drugs / Metabolism | |
| 650 | 4 | |a Drugs / Physiological effect | |
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Datensatz im Suchindex
| _version_ | 1804175966572904448 |
|---|---|
| any_adam_object | |
| author | Coleman, Michael D. |
| author_facet | Coleman, Michael D. |
| author_role | aut |
| author_sort | Coleman, Michael D. |
| author_variant | m d c md mdc |
| building | Verbundindex |
| bvnumber | BV043391349 |
| classification_rvk | VS 5450 |
| collection | ZDB-35-WIC |
| ctrlnum | (ZDB-35-WIC)ocn613339185 (OCoLC)613339185 (DE-599)BVBBV043391349 |
| dewey-full | 615/.7 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.7 |
| dewey-search | 615/.7 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| edition | 2nd ed |
| format | Electronic eBook |
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| id | DE-604.BV043391349 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:24:41Z |
| institution | BVB |
| isbn | 9780470689332 0470689331 9780470689349 047068934X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028809933 |
| oclc_num | 613339185 |
| open_access_boolean | |
| owner | DE-861 |
| owner_facet | DE-861 |
| physical | 1 Online-Ressource (xiv, 346 pages) |
| psigel | ZDB-35-WIC UBG_PDA_WIC ZDB-35-WIC FRO_PDA_WIC ZDB-35-WIC UBG_PDA_WIC |
| publishDate | 2010 |
| publishDateSearch | 2010 |
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| publisher | Wiley-Blackwell |
| record_format | marc |
| spelling | Coleman, Michael D. Verfasser aut Human drug metabolism an introduction Michael D. Coleman 2nd ed Oxford Wiley-Blackwell ©2010 1 Online-Ressource (xiv, 346 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index (Publisher-supplied data) Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of changes in drug metabolism and its impact on patient welfare. After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolizing systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs Pharmaceutical Preparations / metabolism Xenobiotics / toxicity MEDICAL / Pharmacology bisacsh Drugs / Metabolism fast Drugs / Physiological effect fast Medizin Drugs / Metabolism Drugs / Physiological effect Stoffwechselphysiologie (DE-588)4183413-6 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Arzneimittel (DE-588)4003115-9 s Stoffwechselphysiologie (DE-588)4183413-6 s 1\p DE-604 Erscheint auch als Druck-Ausgabe, Hardcover 978-0-470-74217-4 Erscheint auch als Druck-Ausgabe, Hardcover 0-470-74217-8 Erscheint auch als Druck-Ausgabe, Paperback 978-0-470-74216-7 Erscheint auch als Druck-Ausgabe, Paperback 0-470-74216-X https://onlinelibrary.wiley.com/doi/book/10.1002/9780470689332 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Coleman, Michael D. Human drug metabolism an introduction Pharmaceutical Preparations / metabolism Xenobiotics / toxicity MEDICAL / Pharmacology bisacsh Drugs / Metabolism fast Drugs / Physiological effect fast Medizin Drugs / Metabolism Drugs / Physiological effect Stoffwechselphysiologie (DE-588)4183413-6 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4183413-6 (DE-588)4003115-9 |
| title | Human drug metabolism an introduction |
| title_auth | Human drug metabolism an introduction |
| title_exact_search | Human drug metabolism an introduction |
| title_full | Human drug metabolism an introduction Michael D. Coleman |
| title_fullStr | Human drug metabolism an introduction Michael D. Coleman |
| title_full_unstemmed | Human drug metabolism an introduction Michael D. Coleman |
| title_short | Human drug metabolism |
| title_sort | human drug metabolism an introduction |
| title_sub | an introduction |
| topic | Pharmaceutical Preparations / metabolism Xenobiotics / toxicity MEDICAL / Pharmacology bisacsh Drugs / Metabolism fast Drugs / Physiological effect fast Medizin Drugs / Metabolism Drugs / Physiological effect Stoffwechselphysiologie (DE-588)4183413-6 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Pharmaceutical Preparations / metabolism Xenobiotics / toxicity MEDICAL / Pharmacology Drugs / Metabolism Drugs / Physiological effect Medizin Stoffwechselphysiologie Arzneimittel |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9780470689332 |
| work_keys_str_mv | AT colemanmichaeld humandrugmetabolismanintroduction |