The Neuropathology of Huntington's Disease
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Format: | Elektronisch E-Book |
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Sprache: | English |
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Cham
Springer International Publishing
2015
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Schriftenreihe: | Advances in Anatomy, Embryology and Cell Biology
217 |
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Online-Zugang: | DE-91 DE-703 Volltext Inhaltsverzeichnis Abstract |
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245 | 1 | 0 | |a The Neuropathology of Huntington's Disease |c Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf |
264 | 1 | |a Cham |b Springer International Publishing |c 2015 | |
300 | |a 1 Online Ressource (XIV, 146 p. 50 illus., 47 illus. in color) | ||
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490 | 1 | |a Advances in Anatomy, Embryology and Cell Biology |v 217 | |
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700 | 1 | |a Vonsattel, Jean Paul G. |e Sonstige |4 oth | |
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Datensatz im Suchindex
DE-BY-TUM_katkey | 2160200 |
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adam_text | THE NEUROPATHOLOGY OF HUNTINGTON’S DISEASE: CLASSICAL FINDINGS, RECENT
DEVELOPMENTS AND CORRELATION TO FUNCTIONAL NEUROANATOMY
/ RUEB, UDO
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
1. INTRODUCTION
2. THE NEUROPATHOLOGICAL GRADING OF HUNTINGTON DISEASE
3. THE CEREBRAL CORTEX IN HUNTINGTON´S DISEASE
4. DEGENERATION OF SELECT MOTOR AND LIMBIC NUCLEI OF THE THALAMUS IN
HUNTINGTON’S DISEASE
5. CONSISTENT AND WIDESPREAD DEGENERATION OF THE CEREBELLUM IN
HUNTINGTON’S DISEASE
6. ELUCIDATION OF THE ROLE OF THE PREMOTOR OCULOMOTOR BRAINSTEM NUCLEI
IN THE PATHOGENESIS OF OCULOMOTOR DYSFUNCTIONS IN HUNTINGTON’S DISEASE
7. WIDESPREAD BRAINSTEM NEURODEGENERATION IN HUNTINGTON’S DISEASE
8. INTRANEURONAL TRANSPORT AND DEFENSE MECHANISMS WITH POSSIBLE
PATHOGENETIC RELEVANCE IN HUNTINGTON’S DISEASE
9. THE DISEASE PROTEIN HUNTINGTIN AND NEURONAL PROTEIN AGGREGATIONS IN
HUNTINGTON’S DISEASE
10. PATHOLOGICAL NERVE CELL ALTERATIONS IN HUNTINGTON’S DISEASE (HD)
AND THEIR POSSIBLE ROLE FOR THE DEMISE OF NERVE CELLS
11. CONCLUSIONS AND OUTLOOK
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
THE NEUROPATHOLOGY OF HUNTINGTON’S DISEASE: CLASSICAL FINDINGS, RECENT
DEVELOPMENTS AND CORRELATION TO FUNCTIONAL NEUROANATOMY
/ RUEB, UDO
: 2015
ABSTRACT / INHALTSTEXT
THIS MONOGRAPH DESCRIBES THE PROGRESS IN NEUROPATHOLOGICAL HD RESEARCH
MADE DURING THE LAST CENTURY, THE NEUROPATHOLOGICAL HALLMARKS OF HD AND
THEIR PATHOGENIC RELEVANCE. STARTING WITH THE INITIAL DESCRIPTIONS OF
THE PROGRESSIVE DEGENERATION OF THE STRIATUM AS ONE OF THE KEY EVENTS IN
HD, THE WORLDWIDE PRACTICED VONSATTEL HD GRADING SYSTEM OF STRIATAL
NEURODEGENERATION WILL BE OUTLINED. CORRELATING NEUROPATHOLOGICAL DATA
WITH RESULTS ON THE FUNCTIONAL NEUROANATOMY OF THE HUMAN BRAIN,
SUBSEQUENT CHAPTERS WILL HIGHLIGHT RECENT HD FINDINGS: THE NEURONAL LOSS
IN THE CEREBRAL NEO-AND ALLOCORTEX, THE NEURODEGENERATION OF SELECT
THALAMIC NUCLEI, THE AFFECTION OF THE CEREBELLAR CORTEX AND NUCLEI, THE
INVOLVEMENT OF SELECT BRAINSTEM NUCLEI, AS WELL AS THE
PATHOPHYSIOLOGICAL RELEVANCE OF THESE PATHOLOGIES FOR THE CLINICAL
PICTURE OF HD. FINALLY, THE POTENTIAL PATHOPHYSIOLOGICAL ROLE OF
NEURONAL HUNTINGTIN AGGREGATIONS AND THE MOST IMPORTANT AND ENDURING
CHALLENGES OF NEUROPATHOLOGICAL HD RESEARCH ARE DISCUSSED
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
any_adam_object | 1 |
author_GND | (DE-588)1077893108 (DE-588)172131928 (DE-588)115698892 |
building | Verbundindex |
bvnumber | BV043209791 |
classification_tum | BIO 000 |
collection | ZDB-2-SBL |
ctrlnum | (OCoLC)923674834 (DE-599)BVBBV043209791 |
dewey-full | 612.8 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 612 - Human physiology |
dewey-raw | 612.8 |
dewey-search | 612.8 |
dewey-sort | 3612.8 |
dewey-tens | 610 - Medicine and health |
discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-3-319-19285-7 |
format | Electronic eBook |
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id | DE-604.BV043209791 |
illustrated | Not Illustrated |
indexdate | 2024-12-24T04:48:32Z |
institution | BVB |
isbn | 9783319192857 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028632952 |
oclc_num | 923674834 |
open_access_boolean | |
owner | DE-91 DE-BY-TUM DE-703 |
owner_facet | DE-91 DE-BY-TUM DE-703 |
physical | 1 Online Ressource (XIV, 146 p. 50 illus., 47 illus. in color) |
psigel | ZDB-2-SBL ZDB-2-SBL_2015 |
publishDate | 2015 |
publishDateSearch | 2015 |
publishDateSort | 2015 |
publisher | Springer International Publishing |
record_format | marc |
series | Advances in Anatomy, Embryology and Cell Biology |
series2 | Advances in Anatomy, Embryology and Cell Biology |
spellingShingle | The Neuropathology of Huntington's Disease Advances in Anatomy, Embryology and Cell Biology Medicine Human genetics Neurosciences Pathology Biomedicine Human Genetics Medizin |
title | The Neuropathology of Huntington's Disease |
title_auth | The Neuropathology of Huntington's Disease |
title_exact_search | The Neuropathology of Huntington's Disease |
title_full | The Neuropathology of Huntington's Disease Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf |
title_fullStr | The Neuropathology of Huntington's Disease Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf |
title_full_unstemmed | The Neuropathology of Huntington's Disease Udo Rüb, Jean Paul G. Vonsattel, Helmut Heinsen, Horst-Werner Korf |
title_short | The Neuropathology of Huntington's Disease |
title_sort | the neuropathology of huntington s disease |
topic | Medicine Human genetics Neurosciences Pathology Biomedicine Human Genetics Medizin |
topic_facet | Medicine Human genetics Neurosciences Pathology Biomedicine Human Genetics Medizin |
url | https://doi.org/10.1007/978-3-319-19285-7 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028632952&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028632952&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV043279515 |
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