Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates

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Veröffentlicht: Cham Springer International Publishing 2015
Schriftenreihe:Progress in Inflammation Research
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adam_text INFLAMMATORY PATHWAYS IN DIABETES / : 2015 TABLE OF CONTENTS / INHALTSVERZEICHNIS PART 1. INTRODUCTION 1. IMPACT OF INFLAMMATION AND THE INNATE IMMUNITY RESPONSE IN OBESITY MEDIATED DIABETES (LIT REVIEW) PART 2. IMPACT OF COMPLEMENT ON DIABETIC DISEASE 2. COMPLEMENT AND COMPLEMENT REGULATORY PROTEINS IN DIABETES PART 3. ROLE OF C TERMINAL FRAGMENT OF ADIPONECTIN RECEPTOR IN INHIBITION OF INSULIN DEGRADATION 3. DEVELOPMENT OF ADIPONECTIN RECEPTOR C TERMINAL FRAGMENT BIOASSAYS 4. PROTEASE INHIBITION AND BIOLOGICAL DISTRIBUTION OF THE C TERMINAL FRAGMENT OF ADIPONECTIN RECEPTOR 5. CELL & BIOLOGICAL MODELS FOR THE C TERMINAL FRAGMENT OF ADIPONECTIN RECEPTOR 6. C-TERMINAL FRAGMENT OF ADIPONECTIN RECEPTOR CLINICAL CORRELATIONS PART 4. URISTATIN ASSAY FOR PREDICTION OF RENAL AND OTHER CLINICAL EVENTS 7. URISTATIN IMMUNOASSAY USAGE IN GLOMERULAR NEPHRITIS ASSESSMENT 8. ACUTE RESPONSE OF URISTATIN IN SURGERY 9. CARDIOVASCULAR AND METABOLIC SYNDROME IMPACT ON URISTATIN 10. URISTATIN ANTI-INFLAMMATORY CELLULAR SIGNALING PART 5. SUMMARY 11. OVERVIEW OF PROGRESS IN NEW MARKERS FOR DIABETES INFLAMMATION (LITERATUE REVIEW) DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. INFLAMMATORY PATHWAYS IN DIABETES / : 2015 ABSTRACT / INHALTSTEXT THIS BOOK DISCUSSES RECENT ADVANCES IN NEW ANTI- AND PRO-INFLAMMATORY PATHWAYS IN DIABETIC DISEASE, AND IDENTIFIES NEW DIAGNOSTIC IMMUNOLOGICAL METHODS THAT OFFER POTENTIAL COMPANION DIAGNOSTICS FOR DIABETIC DISEASES. NEW METHODS IN PROTEOMICS, MASS SPECTROSCOPY, IMMUNOLOGICAL ASSAY DESIGN, MEASUREMENT OF CELLULAR SIGNAL TRANSDUCTION AND PROTEASE INHIBITION ARE USED TO CLARIFY NEW BIOCHEMICAL PATHWAYS. BIOMARKER VALIDATION IN ANIMAL MODELS AND CORRELATIONS IN HUMANS FOR DIAGNOSTIC CLINICAL TRIALS SHED NEW LIGHT ON THE IMPACT OF DIABETIC DISEASES. THE BOOK REVIEWS CURRENT UNDERSTANDING OF INFLAMMATORY PATHWAYS IN THE PATHOPHYSIOLOGY OF INSULIN RESISTANCE, METABOLIC SYNDROME, NEPHRITIS AND OTHER DIABETIC INFLAMMATORY CONDITIONS, AND IS THE FIRST TO DESCRIBE THE IMPACT OF NOVEL ADIPOKINES, PROTEASE INHIBITORS AND COMPLEMENT MARKERS. BY PRESENTING NEW METHODOLOGIES FOR BIOMARKER DISCOVERY, IT PROVIDES A VALUABLE RESOURCE FOR RESEARCHERS STUDYING CLINICAL DIAGNOSIS, DRUG DEVELOPMENT, BIO-ANALYTICAL CHEMISTRY, PROTEOMICS AND BIOCHEMISTRY. IT IS ALSO USEFUL FOR THOSE CONDUCTING CLINICAL AND BIOLOGICAL STUDIES FOR TARGETED DRUG DEVELOPMENT. THE METHODOLOGIES AND APPROACHES CAN BE APPLIED TO OTHER MARKERS, AND THE INFORMATION WILL BE HELPFUL IN THE PREPARATION OF RESEARCH GRANT APPLICATIONS DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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spellingShingle Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates
Medicine
Immunology
Pharmacology
Diabetes
Metabolic diseases
Biochemistry
Biomedicine
Pharmacology/Toxicology
Metabolic Diseases
Biochemistry, general
Medizin
title Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates
title_auth Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates
title_exact_search Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates
title_full Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates Michael Pugia, ed.
title_fullStr Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates Michael Pugia, ed.
title_full_unstemmed Inflammatory Pathways in Diabetes Biomarkers and Clinical Correlates Michael Pugia, ed.
title_short Inflammatory Pathways in Diabetes
title_sort inflammatory pathways in diabetes biomarkers and clinical correlates
title_sub Biomarkers and Clinical Correlates
topic Medicine
Immunology
Pharmacology
Diabetes
Metabolic diseases
Biochemistry
Biomedicine
Pharmacology/Toxicology
Metabolic Diseases
Biochemistry, general
Medizin
topic_facet Medicine
Immunology
Pharmacology
Diabetes
Metabolic diseases
Biochemistry
Biomedicine
Pharmacology/Toxicology
Metabolic Diseases
Biochemistry, general
Medizin
url https://doi.org/10.1007/978-3-319-21927-1
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