Nucleic acid biosensors for environmental pollution monitoring

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Veröffentlicht: London Royal Society of Chemistry 2011
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500 |a Nucleic acids are the fundamental building blocks of life and are found in all living things. In recent years, their functions have been shown to extend beyond the Watson-Crick base pair recognition of complementary strands. Molecules (known as aptamers) consisting of 40-50 nucleotides have been isolated that are able to bind a broad range of molecules with high affinity and specificity. The molecules recognized by aptamers range from small organic molecules to proteins, cells and even intact viral particles. Catalytic DNA molecules called NAzymes (RNAzyme or DNAzyme) have also been shown to exist and, when combined with aptamers, are known as aptazymes. These biomolecules can be used to develop smart and innovative biosensors for environmental analysis. Monitoring of contaminants in the air, water and soil is a key component in understanding and managing risks to human health and ecosystems. This, in conjunction with the time and cost involved in traditional chemical analysis, means there is a growing need for simple, rapid, cost-effective and portable screening methods. Biosensors are compact devices which complement current field screening and monitoring methods. This book demonstrates the incredible opportunities that nucleic acids can offer to environmental analytical chemistry. The chapters: show how nucleic acids have a pivotal role in the development of smart biosensors for environmental monitoring; describe the development of biosensors based on aptamers and NAzymes for the detection of organic and inorganic pollutants; deal with the use of nucleic acid based biosensors for environmental toxicity screening, and detail the use of nanomaterials, as well as miniaturization and lab-on-a-chip technologies, for nucleic acid based biosensing systems 
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spelling Nucleic acid biosensors for environmental pollution monitoring edited by Marco Mascini and Ilaria Palchetti
London Royal Society of Chemistry 2011
1 Online-Ressource (x, 176 p.)
txt rdacontent
c rdamedia
cr rdacarrier
Includes bibliographical references and index
Nucleic acids are the fundamental building blocks of life and are found in all living things. In recent years, their functions have been shown to extend beyond the Watson-Crick base pair recognition of complementary strands. Molecules (known as aptamers) consisting of 40-50 nucleotides have been isolated that are able to bind a broad range of molecules with high affinity and specificity. The molecules recognized by aptamers range from small organic molecules to proteins, cells and even intact viral particles. Catalytic DNA molecules called NAzymes (RNAzyme or DNAzyme) have also been shown to exist and, when combined with aptamers, are known as aptazymes. These biomolecules can be used to develop smart and innovative biosensors for environmental analysis. Monitoring of contaminants in the air, water and soil is a key component in understanding and managing risks to human health and ecosystems. This, in conjunction with the time and cost involved in traditional chemical analysis, means there is a growing need for simple, rapid, cost-effective and portable screening methods. Biosensors are compact devices which complement current field screening and monitoring methods. This book demonstrates the incredible opportunities that nucleic acids can offer to environmental analytical chemistry. The chapters: show how nucleic acids have a pivotal role in the development of smart biosensors for environmental monitoring; describe the development of biosensors based on aptamers and NAzymes for the detection of organic and inorganic pollutants; deal with the use of nucleic acid based biosensors for environmental toxicity screening, and detail the use of nanomaterials, as well as miniaturization and lab-on-a-chip technologies, for nucleic acid based biosensing systems
SCIENCE / Chemistry / Organic bisacsh
Biosensors fast
Environmental monitoring fast
Nucleic acids / Biotechnology fast
Chemie
Nucleic acids Biotechnology
Biosensors
Environmental monitoring
Mascini, Marco Sonstige oth
Palchetti, Ilaria Sonstige oth
Erscheint auch als Druckausgabe 1-84973-131-4
Erscheint auch als Druckausgabe 978-1-84973-131-7
http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=519334 Aggregator Volltext
spellingShingle Nucleic acid biosensors for environmental pollution monitoring
SCIENCE / Chemistry / Organic bisacsh
Biosensors fast
Environmental monitoring fast
Nucleic acids / Biotechnology fast
Chemie
Nucleic acids Biotechnology
Biosensors
Environmental monitoring
title Nucleic acid biosensors for environmental pollution monitoring
title_auth Nucleic acid biosensors for environmental pollution monitoring
title_exact_search Nucleic acid biosensors for environmental pollution monitoring
title_full Nucleic acid biosensors for environmental pollution monitoring edited by Marco Mascini and Ilaria Palchetti
title_fullStr Nucleic acid biosensors for environmental pollution monitoring edited by Marco Mascini and Ilaria Palchetti
title_full_unstemmed Nucleic acid biosensors for environmental pollution monitoring edited by Marco Mascini and Ilaria Palchetti
title_short Nucleic acid biosensors for environmental pollution monitoring
title_sort nucleic acid biosensors for environmental pollution monitoring
topic SCIENCE / Chemistry / Organic bisacsh
Biosensors fast
Environmental monitoring fast
Nucleic acids / Biotechnology fast
Chemie
Nucleic acids Biotechnology
Biosensors
Environmental monitoring
topic_facet SCIENCE / Chemistry / Organic
Biosensors
Environmental monitoring
Nucleic acids / Biotechnology
Chemie
Nucleic acids Biotechnology
url http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=519334
work_keys_str_mv AT mascinimarco nucleicacidbiosensorsforenvironmentalpollutionmonitoring
AT palchettiilaria nucleicacidbiosensorsforenvironmentalpollutionmonitoring